Detailed information NTG0996072

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ABC965_RS13140
• Genome accession: NZ_CP155063
• Coordinates: 2681846..2682733 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain CC130-MRSA-XI
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2676846..2687733

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC965_RS13110 (ABC965_13110)	-	2676848..2676940 (+)	93	WP_010956583.1	hypothetical protein	-
ABC965_RS13115 (ABC965_13115)	-	2677048..2677545 (-)	498	WP_001065267.1	glutathione peroxidase	-
ABC965_RS13120 (ABC965_13120)	-	2677555..2677815 (-)	261	WP_078103768.1	hypothetical protein	-
ABC965_RS13125 (ABC965_13125)	-	2678197..2678310 (-)	114	WP_072491147.1	hypothetical protein	-
ABC965_RS13130 (ABC965_13130)	-	2678986..2680986 (-)	2001	WP_000776722.1	ABC transporter permease	-
ABC965_RS13135 (ABC965_13135)	-	2680983..2681738 (-)	756	WP_000923770.1	ABC transporter ATP-binding protein	-
ABC965_RS13140 (ABC965_13140)	braS	2681846..2682733 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ABC965_RS13145 (ABC965_13145)	braR	2682744..2683409 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ABC965_RS13150 (ABC965_13150)	-	2683435..2683635 (-)	201	WP_000604725.1	hypothetical protein	-
ABC965_RS13155 (ABC965_13155)	-	2683833..2685257 (+)	1425	WP_000953759.1	alkaline phosphatase	-
ABC965_RS13160 (ABC965_13160)	-	2685327..2685437 (+)	111	WP_001791296.1	hypothetical protein	-
ABC965_RS13165 (ABC965_13165)	-	2685540..2685995 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ABC965_RS13170 (ABC965_13170)	-	2686240..2687001 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=996072 ABC965_RS13140 WP_000143420.1 2681846..2682733(-) (braS) [Staphylococcus aureus strain CC130-MRSA-XI]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=996072 ABC965_RS13140 WP_000143420.1 2681846..2682733(-) (braS) [Staphylococcus aureus strain CC130-MRSA-XI]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993