Detailed information NTG0995805

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: M9Y83_RS27300
• Genome accession: NZ_CP155048
• Coordinates: 5741236..5742573 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain CCBH26428
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5736236..5747573

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M9Y83_RS27275 (M9Y83_0027275)	pgeF	5736379..5737107 (-)	729	WP_012614543.1	peptidoglycan editing factor PgeF	-
M9Y83_RS27280 (M9Y83_0027280)	rluD	5737104..5738066 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
M9Y83_RS27285 (M9Y83_0027285)	-	5738212..5739237 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
M9Y83_RS27290 (M9Y83_0027290)	-	5739394..5739639 (+)	246	WP_003102591.1	PP0621 family protein	-
M9Y83_RS27295 (M9Y83_0027295)	pilS	5739629..5741221 (+)	1593	WP_023129343.1	two-component system sensor histidine kinase PilS	Regulator
M9Y83_RS27300 (M9Y83_0027300)	pilR	5741236..5742573 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
M9Y83_RS27305 (M9Y83_0027305)	thiO	5742619..5743713 (-)	1095	WP_003145981.1	glycine oxidase ThiO	-
M9Y83_RS27310 (M9Y83_0027310)	-	5743848..5744357 (+)	510	WP_003161431.1	Tfp pilus assembly protein FimT/FimU	-
M9Y83_RS27315 (M9Y83_0027315)	-	5744463..5744969 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
M9Y83_RS27320 (M9Y83_0027320)	pilV	5744960..5745517 (+)	558	WP_003094697.1	type 4a pilus minor pilin PilV	Machinery gene
M9Y83_RS27325 (M9Y83_0027325)	pilW	5745514..5746338 (+)	825	WP_128661777.1	type 4a pilus minor pilin PilW	-
M9Y83_RS27330 (M9Y83_0027330)	pilX	5746335..5746922 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=995805 M9Y83_RS27300 WP_003094694.1 5741236..5742573(+) (pilR) [Pseudomonas aeruginosa strain CCBH26428]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=995805 M9Y83_RS27300 WP_003094694.1 5741236..5742573(+) (pilR) [Pseudomonas aeruginosa strain CCBH26428]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384