Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   AAVB50_RS17475 Genome accession   NZ_CP154923
Coordinates   3262246..3262902 (-) Length   218 a.a.
NCBI ID   WP_015383354.1    Uniprot ID   -
Organism   Bacillus subtilis strain FUA2233     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3257246..3267902
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAVB50_RS17450 (AAVB50_17445) spxH 3257458..3258357 (+) 900 WP_024573348.1 protease adaptor protein SpxH -
  AAVB50_RS17455 (AAVB50_17450) - 3258671..3258838 (+) 168 WP_003244944.1 hypothetical protein -
  AAVB50_RS17460 (AAVB50_17455) pepF 3258876..3260705 (-) 1830 WP_003245178.1 oligoendopeptidase F -
  AAVB50_RS17465 (AAVB50_17460) coiA 3260935..3262086 (-) 1152 WP_167408053.1 competence protein CoiA Machinery gene
  AAVB50_RS17470 (AAVB50_17465) - 3262130..3262251 (+) 122 Protein_3393 hypothetical protein -
  AAVB50_RS17475 (AAVB50_17470) mecA 3262246..3262902 (-) 657 WP_015383354.1 adaptor protein MecA Regulator
  AAVB50_RS17480 (AAVB50_17475) - 3262869..3263009 (-) 141 WP_121572562.1 hypothetical protein -
  AAVB50_RS17485 (AAVB50_17480) yjbE 3263179..3263835 (+) 657 WP_003232944.1 TerC family protein -
  AAVB50_RS17490 (AAVB50_17485) spx 3263878..3264273 (-) 396 WP_014476435.1 transcriptional regulator Spx -
  AAVB50_RS17495 (AAVB50_17490) yjbC 3264454..3265032 (-) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  AAVB50_RS17500 (AAVB50_17495) yjbB 3265196..3266413 (-) 1218 WP_088467689.1 MFS transporter -
  AAVB50_RS17505 (AAVB50_17500) oppF 3266519..3267436 (-) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25749.62 Da        Isoelectric Point: 4.0841

>NTDB_id=995555 AAVB50_RS17475 WP_015383354.1 3262246..3262902(-) (mecA) [Bacillus subtilis strain FUA2233]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=995555 AAVB50_RS17475 WP_015383354.1 3262246..3262902(-) (mecA) [Bacillus subtilis strain FUA2233]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995

Multiple sequence alignment