Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   HAS68_RS02280 Genome accession   NZ_CP002007
Coordinates   432314..432955 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis 05HAS68     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 427314..437955
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HAS68_RS02260 (HAS68_0386) - 427483..428220 (+) 738 WP_012774983.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  HAS68_RS02265 (HAS68_0387) stkP 428220..430214 (+) 1995 WP_009909429.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  HAS68_RS02270 (HAS68_0388) liaF 430634..431329 (+) 696 WP_009909430.1 cell wall-active antibiotics response protein LiaF -
  HAS68_RS02275 (HAS68_0389) - 431326..432342 (+) 1017 WP_002937028.1 sensor histidine kinase -
  HAS68_RS02280 (HAS68_0390) vraR 432314..432955 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  HAS68_RS02285 (HAS68_0391) - 433005..434405 (+) 1401 WP_002937018.1 Cof-type HAD-IIB family hydrolase -
  HAS68_RS02290 (HAS68_0392) - 434407..434778 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  HAS68_RS02295 (HAS68_0393) cysK 434805..435731 (-) 927 WP_002937015.1 cysteine synthase A -
  HAS68_RS02300 (HAS68_0394) - 435961..437118 (-) 1158 WP_024409220.1 site-specific integrase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=99524 HAS68_RS02280 WP_002937025.1 432314..432955(+) (vraR) [Streptococcus suis 05HAS68]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=99524 HAS68_RS02280 WP_002937025.1 432314..432955(+) (vraR) [Streptococcus suis 05HAS68]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCTAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCCGCTATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCTTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413

Multiple sequence alignment