Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   AAYR26_RS19930 Genome accession   NZ_CP154901
Coordinates   3694523..3695161 (-) Length   212 a.a.
NCBI ID   WP_009328831.1    Uniprot ID   D9YRK8
Organism   Bacillus licheniformis strain FUA2146     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3689523..3700161
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAYR26_RS19910 (AAYR26_19915) - 3690526..3691242 (+) 717 WP_009328827.1 response regulator -
  AAYR26_RS19915 (AAYR26_19920) - 3691262..3692767 (-) 1506 WP_021837281.1 tripartite tricarboxylate transporter permease -
  AAYR26_RS19920 (AAYR26_19925) - 3692790..3693245 (-) 456 WP_009328829.1 tripartite tricarboxylate transporter TctB family protein -
  AAYR26_RS19925 (AAYR26_19930) - 3693348..3694364 (-) 1017 WP_011197770.1 tripartite tricarboxylate transporter substrate binding protein -
  AAYR26_RS19930 (AAYR26_19935) mecA 3694523..3695161 (-) 639 WP_009328831.1 adaptor protein MecA Regulator
  AAYR26_RS19935 (AAYR26_19940) - 3695143..3695271 (-) 129 Protein_3800 hypothetical protein -
  AAYR26_RS19940 (AAYR26_19945) - 3695447..3696109 (+) 663 WP_009328832.1 TerC family protein -
  AAYR26_RS19945 (AAYR26_19950) spxA 3696332..3696727 (-) 396 WP_009328833.1 transcriptional regulator SpxA -
  AAYR26_RS19950 (AAYR26_19955) - 3696905..3697483 (-) 579 WP_003180619.1 GNAT family N-acetyltransferase -
  AAYR26_RS19955 (AAYR26_19960) - 3697714..3698637 (-) 924 WP_011197769.1 ATP-binding cassette domain-containing protein -
  AAYR26_RS19960 (AAYR26_19965) - 3698639..3699715 (-) 1077 WP_151025719.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 212 a.a.        Molecular weight: 25115.14 Da        Isoelectric Point: 4.2198

>NTDB_id=994952 AAYR26_RS19930 WP_009328831.1 3694523..3695161(-) (mecA) [Bacillus licheniformis strain FUA2146]
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEMMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTRAQL
SKDGQKLELPIPEDKKQHVAEESLDALLDDFQKEEQAEEQKLQFVLKFDDFEDLISLSKMSVSGCQTTLYSHENRYYLFV
DFNELPDEEVENQLSILLEYASESKMTIHMLKEYGKLIAADHALHTIKKHFA

Nucleotide


Download         Length: 639 bp        

>NTDB_id=994952 AAYR26_RS19930 WP_009328831.1 3694523..3695161(-) (mecA) [Bacillus licheniformis strain FUA2146]
ATGGAAATCGAAAGAATAAACGAACACACGGTTAAGTTTTATATTTCCTACGGTGATATCGAAGACCGCGGGTTTGACAG
AGAAGAAATTTGGTACAATCGAGAACGCAGTGAAGAGCTTTTTTGGGAAATGATGGACGAAGTGCACGAAGAAGAAGAGT
TTGCCGTTGAAGGCCCCCTTTGGATTCAAGTGCAGGCCCTTGACAAGGGATTGGAAATCATTGTGACAAGAGCTCAGTTG
TCCAAAGACGGACAAAAGCTGGAACTGCCGATTCCTGAAGATAAAAAACAGCATGTAGCAGAAGAAAGCCTTGATGCTTT
GCTTGACGACTTTCAAAAAGAAGAGCAGGCAGAAGAGCAGAAACTGCAGTTTGTTTTAAAATTTGACGATTTTGAGGATT
TAATCTCACTGTCAAAAATGTCTGTCAGCGGTTGCCAAACGACATTGTACTCTCATGAAAACCGCTATTATTTATTCGTG
GATTTCAATGAACTGCCTGATGAAGAGGTGGAAAACCAGCTGAGCATTCTGCTGGAATATGCTTCAGAATCAAAGATGAC
GATTCATATGCTGAAAGAGTATGGAAAACTGATTGCAGCGGATCATGCTCTTCATACAATAAAAAAGCACTTTGCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D9YRK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

82.949

100

0.849

Multiple sequence alignment