Detailed information NTG0994658

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: AAFU62_RS06690
• Genome accession: NZ_CP154891
• Coordinates: 1374888..1375889 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain 318231
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1369888..1380889

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAFU62_RS06675 (AAFU62_06675)	thrS	1370058..1372001 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
AAFU62_RS06680 (AAFU62_06680)	-	1372423..1373757 (-)	1335	WP_032460075.1	glycosyltransferase family 4 protein	-
AAFU62_RS06685 (AAFU62_06685)	-	1373759..1374757 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
AAFU62_RS06690 (AAFU62_06690)	ccpA	1374888..1375889 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
AAFU62_RS06695 (AAFU62_06695)	-	1376063..1377148 (+)	1086	WP_002985682.1	Xaa-Pro peptidase family protein	-
AAFU62_RS06700 (AAFU62_06700)	-	1377197..1377862 (+)	666	WP_031488435.1	NAD(P)H-dependent oxidoreductase	-
AAFU62_RS06705 (AAFU62_06705)	-	1377873..1378250 (+)	378	WP_002985686.1	VOC family protein	-
AAFU62_RS06710 (AAFU62_06710)	-	1378395..1379321 (+)	927	WP_111689635.1	glycosyltransferase family 2 protein	-
AAFU62_RS06715 (AAFU62_06715)	-	1379532..1380215 (+)	684	WP_136268255.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=994658 AAFU62_RS06690 WP_002985680.1 1374888..1375889(-) (ccpA) [Streptococcus pyogenes strain 318231]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=994658 AAFU62_RS06690 WP_002985680.1 1374888..1375889(-) (ccpA) [Streptococcus pyogenes strain 318231]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559