Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AAYT22_RS01690 Genome accession   NZ_CP154876
Coordinates   326550..327239 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20155336     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 321550..332239
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAYT22_RS01665 (AAYT22_01660) gpsB 321659..321988 (+) 330 WP_000146522.1 cell division regulator GpsB -
  AAYT22_RS01675 (AAYT22_01670) - 322474..323631 (+) 1158 WP_000711392.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  AAYT22_RS01680 (AAYT22_01675) mapZ 323644..325038 (+) 1395 WP_000039283.1 cell division site-positioning protein MapZ -
  AAYT22_RS01685 (AAYT22_01680) gndA 325114..326538 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  AAYT22_RS01690 (AAYT22_01685) covR 326550..327239 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  AAYT22_RS01695 (AAYT22_01690) cbpC 327337..328362 (+) 1026 WP_000698031.1 choline-binding protein CbpC -
  AAYT22_RS01700 (AAYT22_01695) - 328381..329256 (+) 876 WP_000771138.1 choline-binding protein CbpJ -
  AAYT22_RS01705 (AAYT22_01700) - 329374..330606 (-) 1233 WP_000765672.1 MFS transporter -
  AAYT22_RS01710 (AAYT22_01705) - 331136..331474 (-) 339 Protein_333 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=994351 AAYT22_RS01690 WP_000518011.1 326550..327239(+) (covR) [Streptococcus pneumoniae strain 20155336]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=994351 AAYT22_RS01690 WP_000518011.1 326550..327239(+) (covR) [Streptococcus pneumoniae strain 20155336]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment