Detailed information NTG0994236

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: V6C34_RS09595
• Genome accession: NZ_CP154861
• Coordinates: 1958144..1959187 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN31
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1953144..1964187

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6C34_RS09565 (V6C34_09565)	-	1953565..1954821 (-)	1257	WP_001795108.1	aminopeptidase	-
V6C34_RS09570 (V6C34_09570)	-	1954824..1955024 (-)	201	WP_000180460.1	DUF1128 family protein	-
V6C34_RS09575 (V6C34_09575)	-	1955171..1955635 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
V6C34_RS09580 (V6C34_09580)	-	1955642..1955917 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
V6C34_RS09585 (V6C34_09585)	-	1956195..1957412 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
V6C34_RS09590 (V6C34_09590)	vraR	1957525..1958154 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
V6C34_RS09595 (V6C34_09595)	vraS	1958144..1959187 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
V6C34_RS09600 (V6C34_09600)	liaF	1959184..1959885 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
V6C34_RS09605 (V6C34_09605)	-	1959900..1960286 (-)	387	WP_001110179.1	hypothetical protein	-
V6C34_RS09610 (V6C34_09610)	map	1960503..1961261 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
V6C34_RS09615 (V6C34_09615)	-	1961792..1962778 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
V6C34_RS09620 (V6C34_09620)	-	1963209..1963628 (-)	420	WP_196755330.1	hypothetical protein	-
V6C34_RS09625 (V6C34_09625)	-	1963657..1963767 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=994236 V6C34_RS09595 WP_001017131.1 1958144..1959187(-) (vraS) [Staphylococcus aureus strain BSN31]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=994236 V6C34_RS09595 WP_001017131.1 1958144..1959187(-) (vraS) [Staphylococcus aureus strain BSN31]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1