Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   EQB46_RS07560 Genome accession   NZ_LR129843
Coordinates   1399956..1401188 (-) Length   410 a.a.
NCBI ID   WP_000106346.1    Uniprot ID   P63791
Organism   Streptococcus pneumoniae strain 180-2 isolate 180-2     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1394956..1406188
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQB46_RS07530 - 1395146..1396111 (+) 966 WP_000080993.1 NAD(P)/FAD-dependent oxidoreductase -
  EQB46_RS07535 whiA 1396145..1397056 (-) 912 WP_000011276.1 DNA-binding protein WhiA -
  EQB46_RS07540 - 1397053..1398030 (-) 978 WP_001231090.1 YvcK family protein -
  EQB46_RS07545 rapZ 1398027..1398917 (-) 891 WP_000163033.1 RNase adapter RapZ -
  EQB46_RS07550 - 1398969..1399349 (-) 381 WP_001140412.1 RidA family protein -
  EQB46_RS07555 yihA 1399360..1399947 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  EQB46_RS07560 clpX 1399956..1401188 (-) 1233 WP_000106346.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  EQB46_RS07565 - 1401220..1401390 (-) 171 WP_000442275.1 hypothetical protein -
  EQB46_RS07570 - 1401390..1401896 (-) 507 WP_000162487.1 dihydrofolate reductase -
  EQB46_RS07575 - 1402026..1402544 (-) 519 WP_000229874.1 Dps family protein -
  EQB46_RS07580 - 1403041..1404363 (-) 1323 Protein_1445 GH25 family lysozyme -
  EQB46_RS07585 tpiA 1404401..1405159 (-) 759 WP_000087896.1 triose-phosphate isomerase -
  EQB46_RS07590 - 1405256..1405933 (-) 678 WP_000221614.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45798.35 Da        Isoelectric Point: 4.4550

>NTDB_id=993903 EQB46_RS07560 WP_000106346.1 1399956..1401188(-) (clpX) [Streptococcus pneumoniae strain 180-2 isolate 180-2]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=993903 EQB46_RS07560 WP_000106346.1 1399956..1401188(-) (clpX) [Streptococcus pneumoniae strain 180-2 isolate 180-2]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTGGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATTGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterProScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63791

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561