Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   AAIS09_RS09565 Genome accession   NZ_CP154595
Coordinates   1871425..1871751 (-) Length   108 a.a.
NCBI ID   WP_000738638.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain serotype 4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1866425..1876751
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAIS09_RS09520 (AAIS09_09505) rnpA 1866449..1866820 (-) 372 WP_000739246.1 ribonuclease P protein component -
  AAIS09_RS09525 (AAIS09_09510) - 1866837..1866968 (-) 132 WP_000768904.1 hypothetical protein -
  AAIS09_RS09530 (AAIS09_09515) - 1866969..1868159 (-) 1191 WP_000167766.1 acetate kinase -
  AAIS09_RS09535 (AAIS09_09520) comYH 1868210..1869163 (-) 954 WP_000345119.1 class I SAM-dependent methyltransferase Machinery gene
  AAIS09_RS09540 (AAIS09_09525) - 1869224..1869811 (-) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  AAIS09_RS09545 (AAIS09_09530) comGG/cglG 1869948..1870361 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  AAIS09_RS09550 (AAIS09_09535) comGF/cglF 1870339..1870800 (-) 462 WP_000250545.1 competence type IV pilus minor pilin ComGF Machinery gene
  AAIS09_RS09555 (AAIS09_09540) comGE/cglE 1870763..1871065 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  AAIS09_RS09560 (AAIS09_09545) comGD/cglD 1871028..1871432 (-) 405 WP_000588006.1 competence type IV pilus minor pilin ComGD Machinery gene
  AAIS09_RS09565 (AAIS09_09550) comGC/cglC 1871425..1871751 (-) 327 WP_000738638.1 comG operon protein ComGC Machinery gene
  AAIS09_RS09570 (AAIS09_09555) comGB/cglB 1871753..1872769 (-) 1017 WP_075270915.1 competence type IV pilus assembly protein ComGB Machinery gene
  AAIS09_RS09575 (AAIS09_09560) comGA/cglA/cilD 1872717..1873658 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  AAIS09_RS09580 (AAIS09_09565) - 1873734..1874099 (-) 366 WP_000286415.1 DUF1033 family protein -
  AAIS09_RS09585 (AAIS09_09570) - 1874250..1875308 (-) 1059 WP_000649466.1 zinc-dependent alcohol dehydrogenase family protein -
  AAIS09_RS09590 (AAIS09_09575) nagA 1875471..1876622 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12173.35 Da        Isoelectric Point: 10.0523

>NTDB_id=993717 AAIS09_RS09565 WP_000738638.1 1871425..1871751(-) (comGC/cglC) [Streptococcus pneumoniae strain serotype 4]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLQA
DGRITEEQAKAYKEYHDKNGVANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=993717 AAIS09_RS09565 WP_000738638.1 1871425..1871751(-) (comGC/cglC) [Streptococcus pneumoniae strain serotype 4]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAGGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTACAAGCA
GATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGTAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

98.148

100

0.981
  comGC/cglC Streptococcus pneumoniae D39

98.148

100

0.981
  comGC/cglC Streptococcus pneumoniae R6

98.148

100

0.981
  comGC/cglC Streptococcus pneumoniae TIGR4

97.222

100

0.972
  comGC/cglC Streptococcus mitis SK321

94.444

100

0.944
  comGC/cglC Streptococcus mitis NCTC 12261

93.137

94.444

0.88
  comYC Streptococcus gordonii str. Challis substr. CH1

72.917

88.889

0.648
  comYC Streptococcus mutans UA140

63.725

94.444

0.602
  comYC Streptococcus mutans UA159

63.725

94.444

0.602
  comYC Streptococcus suis isolate S10

70.37

75

0.528
  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519
  comGC Staphylococcus aureus MW2

50

79.63

0.398
  comGC Staphylococcus aureus N315

50

79.63

0.398
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment