Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EQB41_RS02235 Genome accession   NZ_LR129840
Coordinates   392278..392910 (+) Length   210 a.a.
NCBI ID   WP_000698443.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4496 isolate 4496     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 387278..397910
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQB41_RS02210 mvaD 387555..388508 (+) 954 WP_127820723.1 diphosphomevalonate decarboxylase -
  EQB41_RS02215 - 388495..389502 (+) 1008 WP_000562380.1 phosphomevalonate kinase -
  EQB41_RS02220 fni 389486..390496 (+) 1011 WP_000210619.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  EQB41_RS02225 liaF 390574..391272 (+) 699 WP_001224638.1 cell wall-active antibiotics response protein LiaF -
  EQB41_RS02230 - 391269..392264 (+) 996 WP_000743677.1 sensor histidine kinase -
  EQB41_RS02235 vraR 392278..392910 (+) 633 WP_000698443.1 response regulator transcription factor Regulator
  EQB41_RS12240 - 392985..393679 (+) 695 Protein_423 DNA alkylation repair protein -
  EQB41_RS02255 - 393829..394068 (+) 240 WP_000754501.1 hypothetical protein -
  EQB41_RS02260 cbpG 394149..394738 (+) 590 Protein_425 choline-binding protein CbpG -
  EQB41_RS02265 - 395040..395432 (+) 393 WP_000378125.1 tyrosine-type recombinase/integrase -
  EQB41_RS02270 tig 395593..396876 (+) 1284 WP_000116469.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23576.07 Da        Isoelectric Point: 4.6491

>NTDB_id=993629 EQB41_RS02235 WP_000698443.1 392278..392910(+) (vraR) [Streptococcus pneumoniae strain 4496 isolate 4496]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEATNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=993629 EQB41_RS02235 WP_000698443.1 392278..392910(+) (vraR) [Streptococcus pneumoniae strain 4496 isolate 4496]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGCGAGGCTACAAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment