Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   E0E08_RS08425 Genome accession   NZ_LR027873
Coordinates   1663378..1664352 (-) Length   324 a.a.
NCBI ID   WP_000697228.1    Uniprot ID   A0A0H2XJS9
Organism   Staphylococcus aureus strain BPH2070 isolate BPH2070     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1658378..1669352
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0E08_RS08380 - 1659076..1659600 (-) 525 WP_001015117.1 shikimate kinase -
  E0E08_RS08385 - 1659590..1659736 (-) 147 WP_001789879.1 hypothetical protein -
  E0E08_RS08390 comGF 1659833..1660330 (-) 498 WP_001803317.1 competence type IV pilus minor pilin ComGF Machinery gene
  E0E08_RS08395 comGE 1660248..1660547 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  E0E08_RS08400 comGD 1660534..1660980 (-) 447 WP_001790850.1 competence type IV pilus minor pilin ComGD Machinery gene
  E0E08_RS08405 comGC 1660958..1661269 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  E0E08_RS08410 comGB 1661283..1661588 (-) 306 WP_332005405.1 type II secretion system F family protein Machinery gene
  E0E08_RS08415 - 1661574..1662746 (+) 1173 WP_000195429.1 IS256-like element IS256 family transposase -
  E0E08_RS08420 - 1662798..1663406 (-) 609 Protein_1582 type II secretion system F family protein -
  E0E08_RS08425 comGA 1663378..1664352 (-) 975 WP_000697228.1 competence type IV pilus ATPase ComGA Machinery gene
  E0E08_RS08430 - 1664404..1665027 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  E0E08_RS08435 - 1665024..1665353 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  E0E08_RS08440 - 1665353..1666339 (-) 987 WP_000161314.1 ROK family glucokinase -
  E0E08_RS08445 - 1666336..1666539 (-) 204 WP_000087561.1 YqgQ family protein -
  E0E08_RS08450 - 1666520..1667983 (-) 1464 WP_001017867.1 rhomboid family protein -
  E0E08_RS08455 - 1667995..1668534 (-) 540 WP_000164545.1 5-formyltetrahydrofolate cyclo-ligase -
  E0E08_RS08460 rpmG 1668743..1668892 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36865.01 Da        Isoelectric Point: 9.0399

>NTDB_id=993128 E0E08_RS08425 WP_000697228.1 1663378..1664352(-) (comGA) [Staphylococcus aureus strain BPH2070 isolate BPH2070]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYLF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQPQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
HKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=993128 E0E08_RS08425 WP_000697228.1 1663378..1664352(-) (comGA) [Staphylococcus aureus strain BPH2070 isolate BPH2070]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCTTTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACCACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGACCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATAAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
CATAAATACATTTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XJS9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

99.074

100

0.991
  comGA Staphylococcus aureus N315

99.074

100

0.991

Multiple sequence alignment