Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACKTXI_RS26475 Genome accession   NZ_AP035884
Coordinates   5939408..5940097 (-) Length   229 a.a.
NCBI ID   WP_030622245.1    Uniprot ID   -
Organism   Streptomyces sp. CMC78     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5934408..5945097
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKTXI_RS26450 (SCMC78_53430) - 5934949..5935212 (-) 264 WP_319600763.1 small hydrophilic protein -
  ACKTXI_RS26455 (SCMC78_53440) - 5935368..5935778 (+) 411 WP_230543879.1 MerR family transcriptional regulator -
  ACKTXI_RS26460 (SCMC78_53450) - 5935778..5936803 (+) 1026 WP_030622238.1 aldo/keto reductase -
  ACKTXI_RS26465 (SCMC78_53460) - 5936842..5938104 (-) 1263 WP_319600765.1 acyltransferase family protein -
  ACKTXI_RS26470 (SCMC78_53470) - 5938101..5939162 (-) 1062 WP_405928449.1 alpha/beta hydrolase -
  ACKTXI_RS26475 (SCMC78_53480) vraR 5939408..5940097 (-) 690 WP_030622245.1 response regulator Regulator
  ACKTXI_RS26480 (SCMC78_53490) - 5940094..5941464 (-) 1371 WP_408054357.1 sensor histidine kinase -
  ACKTXI_RS26485 (SCMC78_53500) - 5941639..5942604 (-) 966 WP_319599607.1 DUF4429 domain-containing protein -
  ACKTXI_RS26490 (SCMC78_53510) - 5942691..5943899 (-) 1209 WP_086779369.1 alpha/beta hydrolase -
  ACKTXI_RS26495 (SCMC78_53520) - 5944076..5944726 (-) 651 WP_319599606.1 TetR family transcriptional regulator -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 24247.90 Da        Isoelectric Point: 5.0891

>NTDB_id=99233 ACKTXI_RS26475 WP_030622245.1 5939408..5940097(-) (vraR) [Streptomyces sp. CMC78]
MTIRVIIVDDQAMVRAGFAALLSAQSDIDVVGEAADGRQGVDVSRNQHPDVVLMDVRMPEMDGLAAARELLNPPVGVVHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLIAAVRVVAAGDALLAPSVTRRLIADFAAQRPAGATRGGQALRLN
GLTPRESEVLELIARGLSNQEIAGRLVLAEQTVKTHIGRVLAKLDLRDRAQAVIFAYESGLVTPGDAGA

Nucleotide


Download         Length: 690 bp        

>NTDB_id=99233 ACKTXI_RS26475 WP_030622245.1 5939408..5940097(-) (vraR) [Streptomyces sp. CMC78]
GTGACCATCCGCGTGATCATCGTCGACGACCAGGCCATGGTGCGGGCCGGGTTCGCGGCGCTGCTGTCGGCGCAGAGCGA
CATCGACGTGGTGGGCGAGGCGGCGGACGGCCGCCAGGGCGTGGACGTCAGCCGCAACCAGCATCCCGACGTGGTCCTGA
TGGACGTCCGGATGCCGGAGATGGACGGACTGGCCGCCGCCCGCGAGCTGTTGAACCCGCCGGTGGGCGTGGTGCACCGG
CCGAAGGTGCTGATGCTGACGACGTTCGACGTGGACGACTACGTGTACGAGGCGCTGCGCGCCGGGGCGTCCGGGTTCCT
GCTGAAGGACGCCCCGCCCGCCGATCTGATCGCGGCGGTACGGGTGGTGGCGGCCGGTGACGCGCTGCTCGCGCCCTCGG
TGACCCGGCGGCTGATCGCGGACTTCGCGGCGCAGCGGCCCGCCGGGGCGACGCGCGGCGGCCAGGCGCTCCGGCTCAAC
GGCCTCACCCCGCGCGAGAGCGAGGTGCTGGAGCTGATCGCCCGGGGGCTGTCGAACCAGGAGATCGCGGGGCGGCTGGT
GCTGGCCGAGCAGACCGTCAAGACGCACATCGGGCGGGTGCTGGCCAAGCTGGACCTGCGGGACCGGGCGCAGGCGGTGA
TCTTCGCGTACGAGTCGGGGCTGGTGACTCCGGGGGACGCGGGGGCGTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(162-216)

Response regulator receiver domain (Response_reg)

(5-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.071

97.817

0.402
  degU Bacillus subtilis subsp. subtilis str. 168

37.004

99.127

0.367

Multiple sequence alignment