Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACKTXI_RS26315 Genome accession   NZ_AP035884
Coordinates   5909488..5910108 (+) Length   206 a.a.
NCBI ID   WP_390445819.1    Uniprot ID   -
Organism   Streptomyces sp. CMC78     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5904488..5915108
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKTXI_RS26290 (SCMC78_53090) - 5904752..5905321 (-) 570 WP_408054349.1 hypothetical protein -
  ACKTXI_RS26295 (SCMC78_53100) - 5905446..5906246 (+) 801 WP_408054350.1 SCO2400 family protein -
  ACKTXI_RS26300 (SCMC78_53110) - 5906382..5907326 (+) 945 WP_319598565.1 ABC transporter ATP-binding protein -
  ACKTXI_RS26305 (SCMC78_53120) - 5907326..5908090 (+) 765 WP_319598566.1 ABC transporter permease -
  ACKTXI_RS26310 (SCMC78_53130) - 5908097..5909491 (+) 1395 WP_408054351.1 sensor histidine kinase -
  ACKTXI_RS26315 (SCMC78_53140) vraR 5909488..5910108 (+) 621 WP_390445819.1 response regulator Regulator
  ACKTXI_RS26320 (SCMC78_53150) - 5910101..5910541 (-) 441 WP_319598569.1 MarR family winged helix-turn-helix transcriptional regulator -
  ACKTXI_RS26325 (SCMC78_53160) - 5910682..5911701 (+) 1020 WP_030078129.1 NADP-dependent oxidoreductase -
  ACKTXI_RS26330 (SCMC78_53170) - 5911814..5912242 (+) 429 WP_006124225.1 organic hydroperoxide resistance protein -
  ACKTXI_RS26335 (SCMC78_53180) - 5912328..5913140 (+) 813 WP_319598571.1 EI24 domain-containing protein -
  ACKTXI_RS26340 (SCMC78_53190) - 5913137..5913745 (+) 609 WP_030622208.1 LysE family transporter -
  ACKTXI_RS26345 (SCMC78_53200) - 5913771..5914778 (-) 1008 WP_319598572.1 aldose epimerase family protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 21976.12 Da        Isoelectric Point: 5.3614

>NTDB_id=99231 ACKTXI_RS26315 WP_390445819.1 5909488..5910108(+) (vraR) [Streptomyces sp. CMC78]
MIRLLIVDDHPVVRGGLRGTFADAEDITVVGEAGDGAEGIERATALTADVVLMDLRMPRMDGVAATAALRERAPDARVLI
LTTFDSESDVLPAIEAGAIGYLLKDALPDELLRAVRAAARGESVLAPSVTQHLMGQVRKPGAGALTDREREVLQLVANGS
SNREAAAALFIGEASIKTHLQHIYDKFGVRDRASAVAEGYRRRLLT

Nucleotide


Download         Length: 621 bp        

>NTDB_id=99231 ACKTXI_RS26315 WP_390445819.1 5909488..5910108(+) (vraR) [Streptomyces sp. CMC78]
ATGATTCGCCTGTTGATCGTTGACGACCATCCGGTGGTACGGGGCGGCCTGCGCGGCACCTTCGCGGACGCCGAGGACAT
CACCGTGGTCGGTGAGGCCGGTGACGGCGCCGAGGGCATCGAACGTGCGACGGCGCTGACCGCGGACGTCGTGCTCATGG
ATCTCCGGATGCCCAGGATGGACGGCGTCGCCGCGACCGCCGCCCTGCGCGAGCGGGCCCCGGATGCCCGCGTGCTGATC
CTGACCACCTTCGACAGCGAGAGCGACGTGCTCCCGGCGATCGAGGCGGGTGCGATCGGCTATCTCCTGAAGGACGCCCT
GCCCGACGAACTGCTGCGCGCGGTCCGCGCGGCCGCGCGCGGGGAGTCGGTGCTCGCGCCGTCGGTGACGCAGCACCTCA
TGGGGCAGGTGCGGAAGCCCGGCGCCGGCGCGCTGACCGACCGGGAGAGGGAGGTGCTGCAACTGGTCGCTAACGGCAGC
TCGAACCGAGAGGCGGCTGCGGCGCTGTTCATCGGCGAAGCGAGCATCAAGACCCATCTGCAGCACATCTACGACAAATT
CGGTGTCCGCGACCGCGCCTCGGCGGTGGCCGAGGGCTACCGCCGCCGCCTGCTCACCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-115)

Bacterial regulatory proteins, luxR family (GerE)

(145-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.806

100

0.398
  degU Bacillus subtilis subsp. subtilis str. 168

37.674

100

0.393

Multiple sequence alignment