Detailed information NTG0099216

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: ACKTXI_RS20485
• Genome accession: NZ_AP035884
• Coordinates: 4585564..4586688 (-)
• Length: 374 a.a.
• NCBI ID: WP_006125491.1
• Uniprot ID: A0ABT7DGV6
• Organism: Streptomyces sp. CMC78
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4580564..4591688

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACKTXI_RS20460 (SCMC78_41470)	cseB	4580818..4581531 (-)	714	WP_193463860.1	two-component system response regulator CseB	-
ACKTXI_RS20465 (SCMC78_41480)	-	4581612..4582295 (-)	684	WP_319288156.1	hypothetical protein	-
ACKTXI_RS20470 (SCMC78_41490)	-	4582424..4583095 (-)	672	WP_381764508.1	SigE family RNA polymerase sigma factor	-
ACKTXI_RS20475 (SCMC78_41500)	-	4583254..4584168 (-)	915	WP_397724463.1	A/G-specific adenine glycosylase	-
ACKTXI_RS20480 (SCMC78_41510)	-	4584471..4585211 (+)	741	WP_408054055.1	hypothetical protein	-
ACKTXI_RS20485 (SCMC78_41520)	disA	4585564..4586688 (-)	1125	WP_006125491.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
ACKTXI_RS20490 (SCMC78_41530)	radA/sms	4586769..4588190 (-)	1422	WP_319601574.1	DNA repair protein RadA	Machinery gene
ACKTXI_RS20495 (SCMC78_41540)	-	4588424..4590304 (+)	1881	WP_408054056.1	BACON domain-containing protein	-
ACKTXI_RS20500 (SCMC78_41550)	-	4590349..4591209 (-)	861	WP_319601435.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40412.35 Da
• Isoelectric Point: 4.9406

>NTDB_id=99216 ACKTXI_RS20485 WP_006125491.1 4585564..4586688(-) (disA) [Streptomyces sp. CMC78]
MAANDRATTPGKSGQGTGNEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDRTVESMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDMTKILRAGVQLVPDASIPTEETGTRHRTADRVSKACGFPVVSVSQSMRLIALYVDGERRVLEESSA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALTELDSLSHTELLELPVVARALGYSGSPETLDSAVSPRGFRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=99216 ACKTXI_RS20485 WP_006125491.1 4585564..4586688(-) (disA) [Streptomyces sp. CMC78]
GTGGCAGCCAACGACCGGGCGACGACGCCCGGAAAGTCCGGCCAAGGCACCGGTAACGAGGCGCTGATGCGCGCCTCGTT
GAGCGCGGTCGCGCCCGGAATGGCCCTGCGGGACGGCCTGGAGCGCATTCTCCGCGGCAATACCGGTGGCCTGATCGTGC
TGGGCATGGACAGAACCGTCGAGTCGATGTGTACCGGCGGATTCGTGCTGGACGTGGAGTTCACGGCGACGCGCCTGCGC
GAGCTGTGCAAGCTCGACGGGGCGCTGATCCTGGACAAGGACATGACCAAGATCCTGCGGGCCGGGGTGCAGCTGGTCCC
GGACGCCTCGATCCCCACGGAGGAGACGGGCACCCGGCACCGTACGGCGGACCGGGTCTCCAAGGCGTGCGGTTTCCCCG
TCGTCTCGGTCTCCCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGGAGCGGCGGGTCCTGGAGGAGTCCTCCGCG
ATCCTGTCCCGGGCCAACCAGGCGCTCGCGACGCTGGAGCGGTACAAGCTGCGCCTCGACGAGGTGGCGGGCACGCTGTC
CGCGCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTGACGGCGGTGGCGCAGCGGCTTGAGATGGTGCGGCGGATCG
CGACGGAGATCGCGGAGTACGTGGTCGAGCTCGGCACCGACGGACGGCTCCTCTCGCTCCAGCTGGACGAGCTGATCGCC
GGGGTGGAGCCGGAGCGGGAGCTGGTCGTCCGGGATTACGTCCCCGAACCGACGGCGAAACGGTCGCGCACGGTGGCCGA
GGCGCTGACCGAGCTGGACTCCCTGAGCCACACGGAGCTGCTGGAGCTGCCGGTGGTGGCGCGGGCGCTGGGCTACAGCG
GCTCGCCGGAGACACTGGACTCGGCGGTGTCGCCGCGGGGCTTCCGGCTGCTGGCGAAGGTGCCGCGGCTGCCGGGGGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGTGGCCTCCAGAAGCTGCTGGCGGCCAGCGTGGACGATCTCCAGACGGTGGA
CGGGGTGGGCGAGGCCCGGGCGCGGAGTGTGCGCGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTGGAACGCTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.152	96.524	0.436