Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACKTXI_RS16170 Genome accession   NZ_AP035884
Coordinates   3641193..3641861 (-) Length   222 a.a.
NCBI ID   WP_030082071.1    Uniprot ID   A0ABW2MQW1
Organism   Streptomyces sp. CMC78     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3636193..3646861
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKTXI_RS16145 (SCMC78_32900) - 3636765..3638048 (-) 1284 WP_030082081.1 adenylosuccinate synthase -
  ACKTXI_RS16150 (SCMC78_32910) - 3638235..3639116 (+) 882 WP_319599959.1 diacylglycerol kinase -
  ACKTXI_RS16155 (SCMC78_32920) - 3639149..3639421 (+) 273 WP_030578653.1 DUF1876 domain-containing protein -
  ACKTXI_RS16160 (SCMC78_32930) - 3639517..3639858 (+) 342 WP_319599958.1 hypothetical protein -
  ACKTXI_RS16165 (SCMC78_32940) - 3639884..3641089 (-) 1206 WP_319599957.1 cytochrome P450 -
  ACKTXI_RS16170 (SCMC78_32950) vraR 3641193..3641861 (-) 669 WP_030082071.1 response regulator Regulator
  ACKTXI_RS16175 (SCMC78_32960) - 3641858..3643210 (-) 1353 WP_319599956.1 sensor histidine kinase -
  ACKTXI_RS16180 (SCMC78_32970) - 3643341..3644168 (-) 828 WP_405929061.1 NAD(P)H-binding protein -
  ACKTXI_RS16185 (SCMC78_32980) - 3644273..3645196 (-) 924 WP_408053873.1 alpha/beta hydrolase -
  ACKTXI_RS16190 (SCMC78_32990) kynU 3645333..3646580 (-) 1248 WP_397725772.1 kynureninase -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 23864.62 Da        Isoelectric Point: 4.6145

>NTDB_id=99204 ACKTXI_RS16170 WP_030082071.1 3641193..3641861(-) (vraR) [Streptomyces sp. CMC78]
MSDTDIRVLIVDDQMMVREGFSVLLNAMPGITVVGEAVDGQQALAQVAALSPDVVLMDIRMPEMNGIEATREIVARDADA
KVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPTVTKRLITEFSKLAETPRPPALARIGDLT
ERETEVLVLIAQGLSNAEIASHLIVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 669 bp        

>NTDB_id=99204 ACKTXI_RS16170 WP_030082071.1 3641193..3641861(-) (vraR) [Streptomyces sp. CMC78]
ATGAGCGACACCGACATCCGGGTCCTGATCGTCGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTCCTGCTCAACGC
GATGCCGGGGATCACCGTCGTGGGCGAGGCGGTGGACGGGCAGCAGGCCCTCGCCCAGGTCGCAGCCCTGAGCCCGGACG
TCGTCCTGATGGACATCCGCATGCCGGAGATGAACGGCATCGAGGCGACCCGCGAGATCGTCGCCCGGGACGCCGACGCG
AAGGTCCTGGTGCTGACGACCTTCGACCTCGACGAGTACGTCTACCAGGCGCTGCGGGCCGGGGCCTCGGGCTTCCTCCT
CAAGGACGCCTCCGCCCGGCAGCTCGCCGACGGGGTACGGGTGGTGGCCTCGGGCGAGGCACTGCTCGCCCCGACGGTCA
CCAAGCGGCTGATCACCGAGTTCTCCAAGCTCGCGGAGACCCCGCGGCCGCCCGCCCTGGCCCGGATCGGCGATCTCACC
GAACGCGAGACGGAGGTGCTCGTCCTGATCGCGCAGGGCCTCTCCAACGCGGAGATCGCCTCGCACCTGATCGTCGCCGA
ATCCACGATCAAGACGCACGTCAGCCGCATCCTGGTGAAGCTGGGGCTGCGCGACCGGACCCAGGCGGCGGTGTTCGCGT
ACGAGGCACGGCTGGTCACCCCGGGGTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-117)

Bacterial regulatory proteins, luxR family (GerE)

(159-213)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.393

96.396

0.428
  degU Bacillus subtilis subsp. subtilis str. 168

42.466

98.649

0.419

Multiple sequence alignment