Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACKTXI_RS09615 Genome accession   NZ_AP035884
Coordinates   2186766..2187416 (+) Length   216 a.a.
NCBI ID   WP_030079302.1    Uniprot ID   -
Organism   Streptomyces sp. CMC78     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2181766..2192416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKTXI_RS09585 (SCMC78_19620) - 2181941..2182582 (-) 642 WP_319598464.1 TetR/AcrR family transcriptional regulator -
  ACKTXI_RS09590 (SCMC78_19630) - 2182691..2183473 (+) 783 WP_319598463.1 ABC transporter ATP-binding protein -
  ACKTXI_RS09595 (SCMC78_19640) - 2183484..2184233 (+) 750 WP_319598462.1 ABC transporter permease -
  ACKTXI_RS09600 (SCMC78_19650) - 2184247..2184819 (+) 573 WP_408053586.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
  ACKTXI_RS09605 (SCMC78_19660) - 2184847..2185419 (-) 573 WP_319598466.1 hypothetical protein -
  ACKTXI_RS09610 (SCMC78_19670) - 2185570..2186769 (+) 1200 WP_319598460.1 sensor histidine kinase -
  ACKTXI_RS09615 (SCMC78_19680) vraR 2186766..2187416 (+) 651 WP_030079302.1 response regulator Regulator
  ACKTXI_RS09620 (SCMC78_19690) - 2187582..2189453 (+) 1872 WP_319598459.1 glycoside hydrolase family 18 chitinase -
  ACKTXI_RS09625 (SCMC78_19700) - 2189563..2190009 (-) 447 WP_030079306.1 DUF2550 domain-containing protein -
  ACKTXI_RS09630 (SCMC78_19710) - 2190143..2190517 (-) 375 WP_010060164.1 F0F1 ATP synthase subunit epsilon -
  ACKTXI_RS09635 (SCMC78_19720) atpD 2190626..2192068 (-) 1443 WP_098024907.1 F0F1 ATP synthase subunit beta -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23044.64 Da        Isoelectric Point: 4.6681

>NTDB_id=99192 ACKTXI_RS09615 WP_030079302.1 2186766..2187416(+) (vraR) [Streptomyces sp. CMC78]
MTIRVLVAEDQSAVRAGLVLILSSAPDIEVVGEAGDGEAAVRLARELRPDLVLMDVQMPRLDGVSATRQVVAEELADVLV
LTTFDLDEYVFGALRAGAAGFLLKNTDARDLLEAVRTVARGEGLIAPAVTRRLIAEFAGATPVRTRETADPAVLDALTRR
EREVLACLGEGLSNAEIALRLSMAEATVKTHVSRLLGKLELRSRVQAAVLAQELGI

Nucleotide


Download         Length: 651 bp        

>NTDB_id=99192 ACKTXI_RS09615 WP_030079302.1 2186766..2187416(+) (vraR) [Streptomyces sp. CMC78]
ATGACGATCCGGGTACTGGTCGCGGAGGACCAGTCGGCGGTGCGCGCGGGGCTGGTGCTGATCCTGTCCAGCGCGCCGGA
CATCGAGGTCGTCGGCGAGGCGGGCGACGGCGAGGCCGCGGTGCGTCTGGCGCGTGAACTCCGCCCGGATCTGGTGCTGA
TGGATGTGCAGATGCCCCGCCTCGACGGGGTGTCGGCGACGCGGCAGGTGGTCGCGGAGGAGCTCGCGGACGTCCTGGTG
CTGACCACGTTCGATCTGGACGAGTACGTCTTCGGGGCGCTGCGCGCGGGGGCCGCCGGCTTTCTGCTGAAGAACACCGA
CGCCCGCGATCTGCTGGAGGCGGTACGGACGGTGGCGCGCGGCGAGGGGCTGATCGCCCCGGCGGTGACCCGGCGGCTGA
TCGCGGAGTTCGCGGGGGCCACGCCCGTACGCACGAGGGAGACGGCCGATCCGGCAGTGCTGGACGCGCTCACCCGGCGC
GAGCGCGAGGTGCTGGCGTGCCTGGGCGAGGGGCTGTCGAACGCGGAGATCGCGCTGCGGCTGTCGATGGCCGAGGCCAC
GGTGAAGACCCATGTCAGCAGGCTGCTGGGCAAGCTGGAGCTGCGCAGCCGGGTTCAGGCGGCCGTTCTCGCCCAGGAGT
TGGGGATCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(156-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.981

98.148

0.412
  degU Bacillus subtilis subsp. subtilis str. 168

39.462

100

0.407

Multiple sequence alignment