Detailed information NTG0099175

Bioinformatically predicted

Overview

• Name: vraR
• Type: Regulator
• Locus tag: ACKTXI_RS05025
• Genome accession: NZ_AP035884
• Coordinates: 1111436..1112083 (+)
• Length: 215 a.a.
• NCBI ID: WP_319599058.1
• Uniprot ID: -
• Organism: Streptomyces sp. CMC78
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1106436..1117083

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACKTXI_RS05005 (SCMC78_10320)	-	1107480..1108283 (+)	804	WP_030084043.1	IclR family transcriptional regulator	-
ACKTXI_RS05010 (SCMC78_10330)	-	1108373..1109053 (-)	681	WP_030084041.1	ABC transporter ATP-binding protein	-
ACKTXI_RS05015 (SCMC78_10340)	-	1109050..1110129 (-)	1080	WP_408053394.1	ABC transporter permease	-
ACKTXI_RS05020 (SCMC78_10350)	-	1110240..1111439 (+)	1200	WP_397720755.1	sensor histidine kinase	-
ACKTXI_RS05025 (SCMC78_10360)	vraR	1111436..1112083 (+)	648	WP_319599058.1	response regulator transcription factor	Regulator
ACKTXI_RS05030 (SCMC78_10370)	-	1112172..1112474 (-)	303	WP_319599071.1	DUF5955 family protein	-
ACKTXI_RS05035 (SCMC78_10380)	-	1112676..1113305 (+)	630	WP_030084031.1	nucleotidyltransferase family protein	-
ACKTXI_RS05040 (SCMC78_10390)	aceB	1113566..1115185 (+)	1620	WP_098026246.1	malate synthase A	-
ACKTXI_RS05045 (SCMC78_10400)	-	1115265..1115906 (-)	642	WP_406192518.1	SMI1/KNR4 family protein	-

Sequence

Protein

• Length: 215 a.a.
• Molecular weight: 22424.70 Da
• Isoelectric Point: 6.3423

>NTDB_id=99175 ACKTXI_RS05025 WP_319599058.1 1111436..1112083(+) (vraR) [Streptomyces sp. CMC78]
MTGGAGAEVIRLLLADDHPVVRAGLRAVLDTEPDFRVAGEAATAEEAVALAAAGGFDVVLMDLQFGTGLHGSEATATITA
LPDGPRVLILTTYDSDADILAAVEAGASGYLLKDAPPQELAAAVRTAAAGRSALAPSVAHRLMDRMRTPAEALTRRELEV
LQLVGEGLSNLQISKRLFLSQATVKSHLVHIYAKLGVDSRTSAVAAATARRLIRR

Nucleotide

• Length: 648 bp

>NTDB_id=99175 ACKTXI_RS05025 WP_319599058.1 1111436..1112083(+) (vraR) [Streptomyces sp. CMC78]
ATGACCGGGGGCGCGGGCGCGGAGGTGATCCGGCTGCTGCTCGCGGACGACCACCCGGTCGTCCGGGCGGGGCTGCGGGC
AGTCCTGGACACCGAGCCGGACTTCCGGGTCGCCGGTGAGGCCGCCACCGCCGAGGAGGCCGTCGCCCTGGCGGCGGCGG
GCGGCTTCGACGTGGTCCTGATGGACCTCCAGTTCGGTACGGGCCTGCACGGCTCGGAGGCCACCGCGACGATCACCGCG
CTGCCGGACGGCCCCCGGGTCCTGATCCTCACCACCTACGACTCCGACGCGGACATCCTGGCGGCGGTCGAGGCCGGGGC
GAGCGGCTATCTGCTCAAGGACGCGCCGCCGCAGGAGCTGGCGGCGGCGGTGCGCACGGCGGCGGCGGGCCGCTCGGCGC
TGGCGCCCTCGGTGGCCCACCGGCTGATGGACCGGATGCGCACCCCGGCCGAGGCGCTGACCCGGCGGGAGCTGGAGGTG
CTCCAGCTGGTCGGGGAGGGCCTGTCGAACCTGCAGATCAGCAAGCGGCTGTTCCTGAGCCAGGCGACGGTGAAGTCCCA
CCTGGTGCACATCTACGCCAAGCTGGGCGTCGACTCGCGTACGTCGGCGGTCGCGGCGGCCACGGCCCGCAGGCTCATCC
GCCGCTGA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, luxR family (GerE) (152-206)

• Response regulator receiver domain (Response_reg) (13-124)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraR	Staphylococcus aureus N315	37.5	96.744	0.363