Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SP4011_RS09680 Genome accession   NZ_AP026968
Coordinates   1944369..1945058 (-) Length   229 a.a.
NCBI ID   WP_338619096.1    Uniprot ID   -
Organism   Streptococcus parapneumoniae strain SP4011     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1939369..1950058
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP4011_RS09675 (SP4011_18700) - 1943353..1944270 (-) 918 WP_338619094.1 N-acetylmuramoyl-L-alanine amidase family protein -
  SP4011_RS09680 (SP4011_18710) covR 1944369..1945058 (-) 690 WP_338619096.1 response regulator transcription factor Regulator
  SP4011_RS09685 (SP4011_18720) gndA 1945070..1946494 (-) 1425 WP_000158785.1 NADP-dependent phosphogluconate dehydrogenase -
  SP4011_RS09690 (SP4011_18730) mapZ 1946570..1947988 (-) 1419 WP_338619097.1 cell division site-positioning protein MapZ -
  SP4011_RS09695 (SP4011_18740) - 1948001..1949158 (-) 1158 WP_338619098.1 class I SAM-dependent RNA methyltransferase -
  SP4011_RS09705 (SP4011_18750) gpsB 1949644..1949985 (-) 342 WP_000146532.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26746.88 Da        Isoelectric Point: 7.3781

>NTDB_id=99134 SP4011_RS09680 WP_338619096.1 1944369..1945058(-) (covR) [Streptococcus parapneumoniae strain SP4011]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNACLGDMTAQDFADKLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIENLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=99134 SP4011_RS09680 WP_338619096.1 1944369..1945058(-) (covR) [Streptococcus parapneumoniae strain SP4011]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTTGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTATTGAATG
CTTGTCTGGGGGATATGACAGCCCAGGATTTTGCAGACAAGCTGAGTCGGACTAAGCCAGCTTCAGTCATCATGGTCTTG
GACCATCGTGAAGAATTGCAAGATCAGATTGAGACAATCCAACGCTTTGCCGTTTCGTACATCTATAAGCCGGTTATTAT
TGAGAATCTGGTAGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTCATCGACCAACACTGTAGTCAGATGAAGGTTC
CAACGTCTTACCGCAATCTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAAGAGATGATTGCCCTGACCCGT
CGTGAGTATGACCTTTTGGCTACTCTTATGGGAAGCAAGAAAGTTCTGACTCGTGAGCAGTTATTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAGACTAATATCGTGGATGTCTATATCCGCTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTTCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467

Multiple sequence alignment