Detailed information NTG0099089

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SP4011_RS01690
• Genome accession: NZ_AP026968
• Coordinates: 302222..303259 (+)
• Length: 345 a.a.
• NCBI ID: WP_000727282.1
• Uniprot ID: -
• Organism: Streptococcus parapneumoniae strain SP4011
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 297222..308259

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP4011_RS01655 (SP4011_02890)	yidC	297256..298182 (-)	927	WP_338619575.1	membrane protein insertase YidC	-
SP4011_RS01660 (SP4011_02900)	-	298260..298538 (-)	279	WP_001174618.1	acylphosphatase	-
SP4011_RS01665 (SP4011_02910)	-	298572..299312 (+)	741	WP_000152696.1	TrmH family RNA methyltransferase	-
SP4011_RS01670 (SP4011_02920)	-	299368..300051 (+)	684	WP_001016914.1	Bax inhibitor-1/YccA family protein	-
SP4011_RS01675 (SP4011_02930)	asnA	300164..301156 (+)	993	WP_000748004.1	aspartate--ammonia ligase	-
SP4011_RS01680 (SP4011_02940)	rsmD	301221..301760 (+)	540	WP_000706954.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SP4011_RS01685 (SP4011_02950)	coaD	301750..302238 (+)	489	WP_001280725.1	pantetheine-phosphate adenylyltransferase	-
SP4011_RS01690 (SP4011_02960)	sepM	302222..303259 (+)	1038	WP_000727282.1	SepM family pheromone-processing serine protease	Regulator
SP4011_RS01695 (SP4011_02970)	-	303317..303547 (+)	231	WP_014017351.1	DUF1146 family protein	-
SP4011_RS01700 (SP4011_02980)	murA	303571..304854 (+)	1284	WP_000358020.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
SP4011_RS01705 (SP4011_02990)	-	304847..305035 (+)	189	WP_044012464.1	DNA-directed RNA polymerase subunit beta	-
SP4011_RS01710 (SP4011_03000)	endA	305074..305898 (+)	825	WP_338619581.1	DNA/RNA non-specific endonuclease	Machinery gene
SP4011_RS01715 (SP4011_03010)	-	306051..307382 (+)	1332	WP_338619583.1	hemolysin family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37517.59 Da
• Isoelectric Point: 5.2365

>NTDB_id=99089 SP4011_RS01690 WP_000727282.1 302222..303259(+) (sepM) [Streptococcus parapneumoniae strain SP4011]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYLGVYVLTVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVNSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVTSDVPIRFSTAGIGGPSAGLMFSL
AIYTQIAHPGLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=99089 SP4011_RS01690 WP_000727282.1 302222..303259(+) (sepM) [Streptococcus parapneumoniae strain SP4011]
ATGAAAAAAAAGATTAGATGGCCCTTATATGTCATTGCGGCCTTAATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
CTACTATATAGAAGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GGGCCTATCAATTCGTTACGGTTGGTGTCCAGCACGCTACTTTAGCCCATATGATTTATGCATGGTTGACGCCTTTTACA
GATATTCGTAGTGCCCAAGAGACTACAGGTGGCTCTTCCGATGTTGAATTTATGCGAATCAATCAATTTTACATGCAAAC
ATCGCAAAATATGGCCAAATATCAAGGGTTAAAAACAGCTGGTAAAGATATCGAACTCAAATACCTTGGGGTTTATGTCT
TGACTGTAACGGATAATTCGACCTTTAAAGGGATTCTCAACATCTCTGATACAGTTACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGATTTGATTGATTACGTCAATTCTCAAAAACTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATTACTCTAGAAAATGGCAAAAATGGGATTGGAATCGGTTTGATTGACCGTA
CAGAAGTGACCAGTGATGTCCCAATTCGCTTTTCAACAGCTGGTATCGGTGGTCCAAGTGCAGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGGTCTTCGTAATGGTCGTATTGTTGCTGGTACAGGTACCATTGACCGTGATGG
GAATGTGGGGGACATTGGTGGTATTGACAAGAAAGTTGTAGCTTCGGCTAGAGCAGGTGCCGCTATTTTCTTTGCTCCTG
ATAACCCAGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAG

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591