Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   SP4011_RS01710 Genome accession   NZ_AP026968
Coordinates   305074..305898 (+) Length   274 a.a.
NCBI ID   WP_338619581.1    Uniprot ID   -
Organism   Streptococcus parapneumoniae strain SP4011     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 300074..310898
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP4011_RS01675 (SP4011_02930) asnA 300164..301156 (+) 993 WP_000748004.1 aspartate--ammonia ligase -
  SP4011_RS01680 (SP4011_02940) rsmD 301221..301760 (+) 540 WP_000706954.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SP4011_RS01685 (SP4011_02950) coaD 301750..302238 (+) 489 WP_001280725.1 pantetheine-phosphate adenylyltransferase -
  SP4011_RS01690 (SP4011_02960) sepM 302222..303259 (+) 1038 WP_000727282.1 SepM family pheromone-processing serine protease Regulator
  SP4011_RS01695 (SP4011_02970) - 303317..303547 (+) 231 WP_014017351.1 DUF1146 family protein -
  SP4011_RS01700 (SP4011_02980) murA 303571..304854 (+) 1284 WP_000358020.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SP4011_RS01705 (SP4011_02990) - 304847..305035 (+) 189 WP_044012464.1 DNA-directed RNA polymerase subunit beta -
  SP4011_RS01710 (SP4011_03000) endA 305074..305898 (+) 825 WP_338619581.1 DNA/RNA non-specific endonuclease Machinery gene
  SP4011_RS01715 (SP4011_03010) - 306051..307382 (+) 1332 WP_338619583.1 hemolysin family protein -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29855.38 Da        Isoelectric Point: 9.8711

>NTDB_id=99090 SP4011_RS01710 WP_338619581.1 305074..305898(+) (endA) [Streptococcus parapneumoniae strain SP4011]
MNKKTRQTLIGLLVLLLLSAGSYYIKQNELGNQAAKTKISQKSQSPDAPSQELAESVLTDAVKSQIKGSLEWNGAGAFIV
NGNKTNLNAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=99090 SP4011_RS01710 WP_338619581.1 305074..305898(+) (endA) [Streptococcus parapneumoniae strain SP4011]
ATGAACAAAAAAACAAGACAGACACTGATTGGCTTGCTAGTGTTATTGCTCTTATCTGCGGGGAGCTATTATATTAAGCA
GAATGAACTAGGCAATCAGGCTGCTAAGACAAAAATAAGTCAGAAAAGTCAATCACCAGACGCGCCTAGTCAAGAATTGG
CAGAAAGTGTCTTAACAGACGCAGTCAAAAGCCAAATAAAAGGGAGTCTGGAGTGGAACGGGGCTGGTGCTTTTATCGTC
AATGGTAATAAAACAAACCTAAATGCCAAGGTTTCAAGTAAGCCCTACGCTGATAATAAGACAAAGACAGTAGGAAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCTACTCGTCAGTACAAGAATCGTGAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCGCAGGCCGAGGATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACTCTTTATTATGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCAGACGGAGAATTGGAATTTAATGTCCTAGTTCCCAATGTTCAAAAAGGGCTTCAACTGGATTACCGAAC
TGGAGAAGTCACTGTTACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

92.701

100

0.927
  endA Streptococcus pneumoniae D39

92.701

100

0.927
  endA Streptococcus pneumoniae R6

92.701

100

0.927
  endA Streptococcus pneumoniae TIGR4

92.701

100

0.927

Multiple sequence alignment