Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   ACGHAS_RS01930 Genome accession   NZ_AP035801
Coordinates   418138..418770 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain E. coli JCM:5491     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 413138..423770
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACGHAS_RS01905 (ReJCM5491_03700) yhfG 413270..413437 (+) 168 WP_000736858.1 YhfG family protein -
  ACGHAS_RS01910 (ReJCM5491_03710) fic 413427..414029 (+) 603 WP_001280638.1 putative adenosine monophosphate-protein transferase Fic -
  ACGHAS_RS01915 (ReJCM5491_03720) pabA 414061..414624 (+) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  ACGHAS_RS01920 (ReJCM5491_03730) argD 414710..415930 (+) 1221 WP_000963800.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  ACGHAS_RS01925 (ReJCM5491_03740) yhfK 415997..418087 (-) 2091 WP_001304921.1 YccS/YhfK family putative transporter -
  ACGHAS_RS01930 (ReJCM5491_03750) crp 418138..418770 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  ACGHAS_RS01935 (ReJCM5491_03760) yhfA 419072..419476 (+) 405 WP_001148908.1 OsmC family protein -
  ACGHAS_RS01940 (ReJCM5491_03770) prkB 419531..420400 (-) 870 WP_001274684.1 phosphoribulokinase -
  ACGHAS_RS01945 (ReJCM5491_03780) yheU 420454..420672 (-) 219 WP_000907085.1 YheU family protein -
  ACGHAS_RS01950 (ReJCM5491_03790) yheT 420666..421688 (-) 1023 WP_000057387.1 hydrolase -
  ACGHAS_RS01955 (ReJCM5491_03800) yheS 421688..423601 (-) 1914 WP_000634808.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=99090 ACGHAS_RS01930 WP_000242755.1 418138..418770(-) (crp) [Escherichia coli strain E. coli JCM:5491]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=99090 ACGHAS_RS01930 WP_000242755.1 418138..418770(-) (crp) [Escherichia coli strain E. coli JCM:5491]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment