Detailed information NTG0990843

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ECRV308_RS02115
• Genome accession: NZ_LM995446
• Coordinates: 420431..421705 (+)
• Length: 424 a.a.
• NCBI ID: WP_000130305.1
• Uniprot ID: P0A6H2
• Organism: Escherichia coli strain K-12 substr. RV308
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 415431..426705

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ECRV308_RS02090 (ECRV308_00410)	yajG	416594..417172 (-)	579	WP_001295326.1	lipoprotein	-
ECRV308_RS02095 (ECRV308_00411)	bolA	417477..417794 (+)	318	WP_000973448.1	transcriptional regulator BolA	-
ECRV308_RS02105 (ECRV308_00412)	tig	418138..419436 (+)	1299	WP_001198386.1	trigger factor	-
ECRV308_RS02110 (ECRV308_00413)	clpP	419682..420305 (+)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
ECRV308_RS02115 (ECRV308_00414)	clpX	420431..421705 (+)	1275	WP_000130305.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
ECRV308_RS02120 (ECRV308_00416)	lon	421893..424247 (+)	2355	WP_001295325.1	endopeptidase La	-
ECRV308_RS02125 (ECRV308_00417)	hupB	424438..424728 (+)	291	WP_254892905.1	nucleoid-associated protein HU-beta	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46356.01 Da
• Isoelectric Point: 4.9982

>NTDB_id=990843 ECRV308_RS02115 WP_000130305.1 420431..421705(+) (clpX) [Escherichia coli strain K-12 substr. RV308]
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIDGQSKPLLIYGKPEAQQASGE

Nucleotide

• Length: 1275 bp

>NTDB_id=990843 ECRV308_RS02115 WP_000130305.1 420431..421705(+) (clpX) [Escherichia coli strain K-12 substr. RV308]
ATGACAGATAAACGCAAAGATGGCTCAGGCAAATTGCTGTATTGCTCTTTTTGCGGCAAAAGCCAGCATGAAGTGCGCAA
GCTGATTGCCGGTCCATCCGTGTATATCTGCGACGAATGTGTTGATTTATGTAACGACATCATTCGCGAAGAGATTAAAG
AAGTTGCACCGCATCGTGAACGCAGTGCGCTACCGACGCCGCATGAAATTCGCAACCACCTGGACGATTACGTTATCGGC
CAGGAACAGGCGAAAAAAGTGCTGGCGGTCGCGGTATACAACCATTACAAACGTCTGCGCAACGGCGATACCAGCAATGG
CGTCGAGTTGGGCAAAAGTAACATTCTGCTGATCGGTCCGACCGGTTCCGGTAAAACGCTGCTGGCTGAAACGCTGGCGC
GCCTGCTGGATGTTCCGTTCACCATGGCCGACGCGACTACACTGACCGAAGCCGGTTATGTGGGTGAAGACGTTGAAAAC
ATCATTCAGAAGCTGTTGCAGAAATGCGACTACGATGTCCAGAAAGCACAGCGTGGTATTGTCTACATCGATGAAATCGA
CAAGATTTCTCGTAAGTCAGACAACCCGTCCATTACCCGAGACGTTTCCGGTGAAGGCGTACAGCAGGCACTGTTGAAAC
TGATCGAAGGTACGGTAGCTGCTGTTCCACCGCAAGGTGGGCGTAAACATCCGCAGCAGGAATTCTTGCAGGTTGATACC
TCTAAGATCCTGTTTATTTGTGGCGGTGCGTTTGCCGGTCTGGATAAAGTGATTTCCCACCGTGTAGAAACCGGCTCCGG
CATTGGTTTTGGCGCGACGGTAAAAGCGAAGTCCGACAAAGCAAGCGAAGGCGAGCTGCTGGCGCAGGTTGAACCGGAAG
ATCTGATCAAGTTTGGTCTTATCCCTGAGTTTATTGGTCGTCTGCCGGTTGTCGCAACGTTGAATGAACTGAGCGAAGAA
GCTCTGATTCAGATCCTCAAAGAGCCGAAAAACGCCCTGACCAAGCAGTATCAGGCGCTGTTTAATCTGGAAGGCGTGGA
TCTGGAATTCCGTGACGAGGCGCTGGATGCTATCGCTAAGAAAGCGATGGCGCGTAAAACCGGTGCCCGTGGCCTGCGTT
CCATCGTAGAAGCCGCACTGCTCGATACCATGTACGATCTGCCGTCCATGGAAGACGTCGAAAAAGTGGTTATCGACGAG
TCGGTAATTGATGGTCAAAGCAAACCGTTGCTGATTTATGGCAAGCCGGAAGCGCAACAGGCATCTGGTGAATAA

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (112-310)

3D structure

• AlphaFold DB: P0A6H2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.85	94.575	0.566
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.392	96.226	0.533