Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGG/cglG   Type   Machinery gene
Locus tag   SP4011_RS01285 Genome accession   NZ_AP026968
Coordinates   227397..227810 (+) Length   137 a.a.
NCBI ID   WP_000265635.1    Uniprot ID   -
Organism   Streptococcus parapneumoniae strain SP4011     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 228272..236321 227397..227810 flank 462


Gene organization within MGE regions


Location: 227397..236321
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP4011_RS01285 (SP4011_02300) comGG/cglG 227397..227810 (+) 414 WP_000265635.1 competence type IV pilus minor pilin ComGG Machinery gene
  SP4011_RS01290 (SP4011_02310) - 228272..229114 (-) 843 WP_000840058.1 helix-turn-helix domain-containing protein -
  SP4011_RS01295 (SP4011_02320) - 229311..229787 (-) 477 WP_000777684.1 GNAT family N-acetyltransferase -
  SP4011_RS01300 (SP4011_02330) - 229900..231102 (-) 1203 WP_000855226.1 ATP-grasp domain-containing protein -
  SP4011_RS01305 (SP4011_02340) - 231104..232003 (-) 900 WP_000771264.1 hypothetical protein -
  SP4011_RS01310 (SP4011_02350) - 232004..233065 (-) 1062 WP_000604329.1 ATP-grasp domain-containing protein -
  SP4011_RS01315 (SP4011_02360) - 233209..234192 (-) 984 WP_000864435.1 hypothetical protein -
  SP4011_RS01320 (SP4011_02370) - 234167..235186 (-) 1020 WP_000612003.1 pyridoxal-phosphate dependent enzyme -

Sequence


Protein


Download         Length: 137 a.a.        Molecular weight: 15979.50 Da        Isoelectric Point: 10.1696

>NTDB_id=99083 SP4011_RS01285 WP_000265635.1 227397..227810(+) (comGG/cglG) [Streptococcus parapneumoniae strain SP4011]
MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVVHHRDYALNKEKLIAFAMAKRTKDKVEQESGEQVYNLGQVSYQNKK
TSLVTTVRTPKSQYEFLFPSVKIKEEKKDKKEEVATDSSEKVEKKKSEEELEKKENS

Nucleotide


Download         Length: 414 bp        

>NTDB_id=99083 SP4011_RS01285 WP_000265635.1 227397..227810(+) (comGG/cglG) [Streptococcus parapneumoniae strain SP4011]
GTGTGGAAAAAGAAAAAAGTTAAGGCAGGTGTTCTCCTCTATGCAGTCACCATGGCAGCCATCTTTAGTCTTTTGTTACA
ATTTTACTTGAACCGACAAGTCGTCCACCATCGAGACTATGCTTTAAATAAAGAAAAGTTAATTGCTTTTGCCATGGCCA
AGCGAACCAAAGATAAGGTTGAGCAAGAAAGTGGAGAACAGGTTTATAACCTAGGTCAGGTGAGCTATCAAAATAAGAAA
ACAAGCTTGGTGACGACGGTTCGTACGCCTAAGAGTCAATATGAGTTCCTATTTCCCTCAGTCAAAATCAAAGAAGAGAA
AAAGGATAAAAAGGAGGAGGTAGCGACCGATTCAAGCGAAAAAGTAGAGAAGAAAAAATCAGAAGAGGAGCTTGAAAAGA
AAGAGAATTCCTAG

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGG/cglG Streptococcus mitis SK321

84.672

100

0.847

  comGG/cglG Streptococcus mitis NCTC 12261

88.43

88.321

0.781

  comGG/cglG Streptococcus pneumoniae D39

90.598

85.401

0.774

  comGG/cglG Streptococcus pneumoniae TIGR4

90.598

85.401

0.774

  comGG/cglG Streptococcus pneumoniae R6

90.598

85.401

0.774

  comGG/cglG Streptococcus pneumoniae Rx1

90.598

85.401

0.774

  comYG Streptococcus mutans UA140

39.231

94.891

0.372

  comYG Streptococcus mutans UA159

39.231

94.891

0.372


Multiple sequence alignment