Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   HMPREF9319_RS01855 Genome accession   NZ_GL397128
Coordinates   375908..376552 (+) Length   214 a.a.
NCBI ID   WP_003063534.1    Uniprot ID   E0PBZ7
Organism   Streptococcus equinus ATCC 700338     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 370908..381552
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9319_RS01835 (HMPREF9319_0366) - 371495..372232 (+) 738 WP_003063530.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  HMPREF9319_RS01840 (HMPREF9319_0367) pknB 372232..374112 (+) 1881 WP_003063531.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  HMPREF9319_RS01845 (HMPREF9319_0368) liaF 374207..374902 (+) 696 WP_003063532.1 cell wall-active antibiotics response protein LiaF -
  HMPREF9319_RS01850 (HMPREF9319_0369) - 374899..375924 (+) 1026 WP_003063533.1 sensor histidine kinase -
  HMPREF9319_RS01855 (HMPREF9319_0370) vraR 375908..376552 (+) 645 WP_003063534.1 response regulator Regulator
  HMPREF9319_RS01860 (HMPREF9319_0371) - 376670..378070 (+) 1401 WP_003063536.1 Cof-type HAD-IIB family hydrolase -
  HMPREF9319_RS01865 (HMPREF9319_0372) - 378070..378426 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -
  HMPREF9319_RS01870 (HMPREF9319_0373) cysK 378539..379468 (-) 930 WP_003063544.1 cysteine synthase A -
  HMPREF9319_RS01875 (HMPREF9319_0374) - 379572..380198 (-) 627 WP_003063547.1 YigZ family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23941.65 Da        Isoelectric Point: 4.6582

>NTDB_id=989380 HMPREF9319_RS01855 WP_003063534.1 375908..376552(+) (vraR) [Streptococcus equinus ATCC 700338]
MTQKIRVTLVDDHEMVRLGLKSFLNLQPDVEVVGEAGNGLDGINLALELKPDVVVMDLVMPEMSGVEATLKLLEEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVARGELAIETEVDKKIKAHDMQPELHDDLTARERDILRLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=989380 HMPREF9319_RS01855 WP_003063534.1 375908..376552(+) (vraR) [Streptococcus equinus ATCC 700338]
ATGACCCAGAAAATTAGAGTTACCCTAGTAGATGATCATGAAATGGTACGTTTAGGGTTAAAAAGCTTTTTGAATTTGCA
ACCAGATGTTGAGGTGGTCGGCGAAGCTGGAAATGGTTTAGACGGCATTAATTTGGCTTTAGAATTAAAACCAGATGTGG
TTGTTATGGATTTGGTAATGCCAGAAATGAGCGGTGTCGAAGCGACATTGAAGCTTCTGGAAGAATGGAAAGAAGCTAAG
ATTCTTGTCTTAACATCTTACCTTGATAATGAAAAAATTTATCCTGTCATTGAAGCAGGTGCTAAAGGTTATATGTTAAA
AACATCTAGCGCAGCAGAAATTTTAAATGCCATTCAGAAAGTTGCACGTGGTGAGTTAGCTATTGAAACAGAAGTCGATA
AAAAAATCAAAGCTCATGATATGCAACCAGAATTGCATGACGATTTGACAGCGCGTGAACGTGATATTTTGAGATTACTT
GCTAAAGGGTATGATAACCAAACTATTGCTGATGAGTTATTTATCTCACTAAAGACCGTCAAAACACACGTTTCAAATAT
TCTAGCTAAGTTAGAAGTCGATGATCGTACACAAGCAGTCGTTTACGCCTTTAAACATCATTTAGTACCGCAAGATGACG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-119)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E0PBZ7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.456

96.262

0.495
  degU Bacillus subtilis subsp. subtilis str. 168

37.5

100

0.393

Multiple sequence alignment