Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R8570_RS09815 Genome accession   NZ_AP026932
Coordinates   1925459..1926412 (-) Length   317 a.a.
NCBI ID   WP_000345086.1    Uniprot ID   A0A064C057
Organism   Streptococcus pneumoniae strain PZ900701549     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1920459..1931412
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8570_RS09790 (PC1528_19300) - 1921221..1921844 (-) 624 WP_000932660.1 hypothetical protein -
  R8570_RS09795 (PC1528_19310) jag 1921895..1922881 (-) 987 WP_050263793.1 RNA-binding cell elongation regulator Jag/EloR -
  R8570_RS09800 (PC1528_19320) - 1922900..1923724 (-) 825 WP_201417363.1 membrane protein insertase YidC -
  R8570_RS09805 (PC1528_19330) rnpA 1923699..1924070 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R8570_RS09810 (PC1528_19340) - 1924218..1925408 (-) 1191 WP_000167755.1 acetate kinase -
  R8570_RS09815 (PC1528_19350) comYH 1925459..1926412 (-) 954 WP_000345086.1 class I SAM-dependent methyltransferase Machinery gene
  R8570_RS09820 - 1926473..1927060 (-) 588 Protein_1910 class I SAM-dependent methyltransferase -
  R8570_RS09825 (PC1528_19380) comGG/cglG 1927197..1927610 (-) 414 WP_000265617.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8570_RS09830 (PC1528_19390) comGF/cglF 1927588..1928049 (-) 462 WP_000250529.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8570_RS09835 (PC1528_19400) comGE/cglE 1928012..1928314 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8570_RS09840 (PC1528_19410) comGD/cglD 1928277..1928681 (-) 405 WP_000588002.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8570_RS09845 (PC1528_19420) comGC/cglC 1928674..1929000 (-) 327 WP_000738623.1 comG operon protein ComGC Machinery gene
  R8570_RS09850 (PC1528_19430) comGB/cglB 1929002..1930018 (-) 1017 WP_077141332.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8570_RS09855 (PC1528_19440) comGA/cglA/cilD 1929966..1930907 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  R8570_RS09860 (PC1528_19450) - 1930983..1931348 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35676.86 Da        Isoelectric Point: 4.2270

>NTDB_id=98924 R8570_RS09815 WP_000345086.1 1925459..1926412(-) (comYH) [Streptococcus pneumoniae strain PZ900701549]
MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGFKYLKSDGYAIFLAPSDLLTSPQ
SDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=98924 R8570_RS09815 WP_000345086.1 1925459..1926412(-) (comYH) [Streptococcus pneumoniae strain PZ900701549]
ATGGATTTTGAAAAAATTGAACAAGCTTATATCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACGCCAGATGCTATTGCCTTACTTTTGGTATTTATTGTGGAAGAGTTGTTTAC
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGCCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCTCATCACTTGCTCA
TGGAACAAGGGTTTAAGTACCTTAAGTCAGATGGATATGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064C057

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment