Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AAFQ93_RS04325 Genome accession   NZ_CP152419
Coordinates   896667..897356 (+) Length   229 a.a.
NCBI ID   WP_045763606.1    Uniprot ID   A0A0F3HBF4
Organism   Streptococcus nidrosiense strain SO-23-1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 891667..902356
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAFQ93_RS04300 (AAFQ93_04290) gpsB 891711..892040 (+) 330 WP_000146538.1 cell division regulator GpsB -
  AAFQ93_RS04310 (AAFQ93_04300) - 892521..893678 (+) 1158 WP_375555699.1 class I SAM-dependent RNA methyltransferase -
  AAFQ93_RS04315 (AAFQ93_04305) - 893691..895154 (+) 1464 WP_375555700.1 cell division site-positioning protein MapZ family protein -
  AAFQ93_RS04320 (AAFQ93_04310) gndA 895231..896655 (+) 1425 WP_003017375.1 NADP-dependent phosphogluconate dehydrogenase -
  AAFQ93_RS04325 (AAFQ93_04315) covR 896667..897356 (+) 690 WP_045763606.1 response regulator transcription factor Regulator
  AAFQ93_RS04330 (AAFQ93_04320) cbpJ 897453..898379 (+) 927 WP_375555701.1 choline-binding protein CbpJ -
  AAFQ93_RS04335 (AAFQ93_04325) mvk 898502..899380 (+) 879 WP_375555702.1 mevalonate kinase -
  AAFQ93_RS04340 (AAFQ93_04330) mvaD 899362..900315 (+) 954 WP_375555703.1 diphosphomevalonate decarboxylase -
  AAFQ93_RS04345 (AAFQ93_04335) - 900302..901315 (+) 1014 WP_375555704.1 phosphomevalonate kinase -
  AAFQ93_RS04350 (AAFQ93_04340) fni 901293..902294 (+) 1002 WP_375555705.1 type 2 isopentenyl-diphosphate Delta-isomerase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26765.87 Da        Isoelectric Point: 7.0639

>NTDB_id=989166 AAFQ93_RS04325 WP_045763606.1 896667..897356(+) (covR) [Streptococcus nidrosiense strain SO-23-1]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNAHLGDMTAQDFADKLSRTKPAAVIMVL
DHREELQDQLETIQRFAVSYIYKPIIIDDLVSRISAIFRGRDFIDQHCSQMKVPTAYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLIESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=989166 AAFQ93_RS04325 WP_045763606.1 896667..897356(+) (covR) [Streptococcus nidrosiense strain SO-23-1]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAAAGAAATCTAGCTCATTTTTTAAGTCTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTAGAAGAGGGACAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTACTGAATG
CTCATCTAGGGGATATGACAGCCCAGGATTTTGCAGATAAGTTGAGTCGAACCAAGCCAGCTGCGGTTATCATGGTCTTG
GACCATCGAGAAGAATTGCAAGACCAACTTGAAACAATCCAGCGTTTCGCTGTTTCATACATCTATAAACCAATCATTAT
TGATGATTTGGTCAGTCGTATTTCAGCTATCTTCCGAGGTCGAGATTTCATCGATCAACACTGTAGTCAGATGAAAGTTC
CGACAGCTTATCGCAATCTGCGTATGGATGTTGAACATCATACCGTCTATCGTGGCGAGGAGATGATTGCTCTGACACGT
CGTGAATATGACCTCTTAGCTACACTCATGGGTAGTAAAAAAGTCTTAACTCGTGAACAATTGATAGAGAGTGTCTGGAA
GTATGAAAGTGCGACCGAAACCAATATTGTGGACGTTTATATCCGTTATCTACGTAGCAAACTTGACGTGAAAGGTCAAA
AGAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F3HBF4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.614

99.563

0.454

Multiple sequence alignment