Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   AAHH81_RS06955 Genome accession   NZ_CP152418
Coordinates   1381700..1382932 (-) Length   410 a.a.
NCBI ID   WP_000106340.1    Uniprot ID   A0AA94UQP3
Organism   Streptococcus pneumoniae strain 20234287     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1376700..1387932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAHH81_RS06925 (AAHH81_06910) - 1376890..1377855 (+) 966 WP_061813595.1 NAD(P)/FAD-dependent oxidoreductase -
  AAHH81_RS06930 (AAHH81_06915) whiA 1377889..1378800 (-) 912 WP_100104578.1 DNA-binding protein WhiA -
  AAHH81_RS06935 (AAHH81_06920) - 1378797..1379774 (-) 978 WP_001231073.1 YvcK family protein -
  AAHH81_RS06940 (AAHH81_06925) rapZ 1379771..1380661 (-) 891 WP_374918017.1 RNase adapter RapZ -
  AAHH81_RS06945 (AAHH81_06930) - 1380713..1381093 (-) 381 WP_001140420.1 RidA family protein -
  AAHH81_RS06950 (AAHH81_06935) yihA 1381104..1381691 (-) 588 WP_000405202.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  AAHH81_RS06955 (AAHH81_06940) clpX 1381700..1382932 (-) 1233 WP_000106340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  AAHH81_RS06960 (AAHH81_06945) - 1382964..1383134 (-) 171 WP_374918018.1 hypothetical protein -
  AAHH81_RS06965 (AAHH81_06950) - 1383134..1383640 (-) 507 WP_374918019.1 dihydrofolate reductase -
  AAHH81_RS06970 (AAHH81_06955) - 1383770..1384288 (-) 519 WP_374918020.1 Dps family protein -
  AAHH81_RS06975 (AAHH81_06960) lytC 1384785..1386290 (-) 1506 WP_078158795.1 choline binding-anchored murein hydrolase LytC -
  AAHH81_RS06980 (AAHH81_06965) tpiA 1386328..1387086 (-) 759 WP_000087898.1 triose-phosphate isomerase -
  AAHH81_RS06985 (AAHH81_06970) - 1387184..1387861 (-) 678 WP_000221614.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45754.30 Da        Isoelectric Point: 4.4550

>NTDB_id=989075 AAHH81_RS06955 WP_000106340.1 1381700..1382932(-) (clpX) [Streptococcus pneumoniae strain 20234287]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTIDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=989075 AAHH81_RS06955 WP_000106340.1 1381700..1382932(-) (clpX) [Streptococcus pneumoniae strain 20234287]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGGAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTGGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATCGAACTCCTCCATATCTTGAACCACTATGTAATCGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGTATCAACTTCCACGATACGCGTGAGGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTGCCTTTTGCGATTGCGGATGCGACAGCTCTTACTGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATTCTCCTTAAACTCTTGCAGGCTGCTGACTTTAATATCGAGCGTGCAGAGCGTGGGATTATCTACGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGCGAGAACGTATCGATCACACGGGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCGCAACAAGAAATGATTCAAGTGGATACT
AAAAATATCCTCTTCATCGTGGGTGGTGCCTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAGGTTAT
CGGCTTTGGTCAAAATAATAAAGCAATTGATGAAAACAGCTCTTACATGCAAGAAATCATCGCAGAAGATATTCAAAAAT
TCGGTATTATTCCAGAGTTGATTGGACGCTTGCCTGTCTTTGCAGCCCTTGAGCAATTAACGATTGATGACTTGGTTCGT
ATCTTGAAAGAGCCAAGAAATGCCTTGGTCAAACAATATCAAACCTTGTTATCTTATGATGATGTCGAGTTGGAATTTGA
CGACGAAGCTCTTCAAGAGATTGCCAATAAGGCCATCGAACGGAAGACAGGGGCGCGTGGTCTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTCATGTTTGAAGTACCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACAAAAGAAGCTGTCGAT
GGAACGGATAAACCAATCTTGGAAACAGCCTAG

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.829

100

0.868
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.463

98.049

0.563

Multiple sequence alignment