Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   R8570_RS07370 Genome accession   NZ_AP026932
Coordinates   1465771..1467003 (-) Length   410 a.a.
NCBI ID   WP_001863391.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701549     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1460771..1472003
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8570_RS07340 (PC1528_14790) - 1460958..1461926 (+) 969 WP_050263740.1 NAD(P)/FAD-dependent oxidoreductase -
  R8570_RS07345 (PC1528_14800) whiA 1461960..1462871 (-) 912 WP_000011306.1 DNA-binding protein WhiA -
  R8570_RS07350 (PC1528_14810) - 1462868..1463845 (-) 978 WP_001231086.1 YvcK family protein -
  R8570_RS07355 (PC1528_14820) rapZ 1463842..1464732 (-) 891 WP_000163033.1 RNase adapter RapZ -
  R8570_RS07360 (PC1528_14830) - 1464784..1465164 (-) 381 WP_001140412.1 RidA family protein -
  R8570_RS07365 (PC1528_14840) yihA 1465175..1465762 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  R8570_RS07370 (PC1528_14850) clpX 1465771..1467003 (-) 1233 WP_001863391.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  R8570_RS07375 - 1467035..1467205 (-) 171 WP_000442275.1 hypothetical protein -
  R8570_RS07380 (PC1528_14860) - 1467205..1467711 (-) 507 WP_050263737.1 dihydrofolate reductase -
  R8570_RS07385 (PC1528_14870) - 1467841..1468359 (-) 519 WP_050263735.1 DNA starvation/stationary phase protection protein -
  R8570_RS07390 (PC1528_14880) lytC 1468855..1470360 (-) 1506 WP_075575672.1 choline binding-anchored murein hydrolase LytC -
  R8570_RS07395 (PC1528_14890) tpiA 1470398..1471156 (-) 759 WP_000087897.1 triose-phosphate isomerase -
  R8570_RS07400 (PC1528_14900) - 1471254..1471931 (-) 678 WP_050263733.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45740.31 Da        Isoelectric Point: 4.4775

>NTDB_id=98901 R8570_RS07370 WP_001863391.1 1465771..1467003(-) (clpX) [Streptococcus pneumoniae strain PZ900701549]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDANSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=98901 R8570_RS07370 WP_001863391.1 1465771..1467003(-) (clpX) [Streptococcus pneumoniae strain PZ900701549]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGCAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTAGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATTGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.965

98.049

0.559

Multiple sequence alignment