Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACNR93_RS02410 Genome accession   NZ_CP184736
Coordinates   461772..462416 (+) Length   214 a.a.
NCBI ID   WP_024344653.1    Uniprot ID   -
Organism   Streptococcus equinus strain NM-2-29     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 456772..467416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNR93_RS02390 (ACNR93_02390) - 457316..458053 (+) 738 WP_024344649.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACNR93_RS02395 (ACNR93_02395) pknB 458053..459927 (+) 1875 WP_420543810.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ACNR93_RS02400 (ACNR93_02400) liaF 460071..460766 (+) 696 WP_420543811.1 cell wall-active antibiotics response protein LiaF -
  ACNR93_RS02405 (ACNR93_02405) - 460763..461788 (+) 1026 WP_021141792.1 sensor histidine kinase -
  ACNR93_RS02410 (ACNR93_02410) vraR 461772..462416 (+) 645 WP_024344653.1 response regulator transcription factor Regulator
  ACNR93_RS02415 (ACNR93_02415) - 462540..463940 (+) 1401 WP_029876003.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ACNR93_RS02420 (ACNR93_02420) - 463940..464296 (+) 357 WP_027968108.1 S1 RNA-binding domain-containing protein -
  ACNR93_RS02425 (ACNR93_02425) cysK 464370..465299 (-) 930 WP_420543812.1 cysteine synthase A -
  ACNR93_RS02430 (ACNR93_02430) - 465397..466023 (-) 627 WP_420543813.1 YigZ family protein -
  ACNR93_RS02435 (ACNR93_02435) comFA/cflA 466078..467376 (+) 1299 WP_420543814.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23992.85 Da        Isoelectric Point: 5.1944

>NTDB_id=988871 ACNR93_RS02410 WP_024344653.1 461772..462416(+) (vraR) [Streptococcus equinus strain NM-2-29]
MTQKIRVILVDDHEMVRLGLKSFFNLQPDVEVVGEAGNGIDGIKLALELKPDVVVMDLVMPEMSGVEATLKLLKEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIHKVARGDLAIETEVDKKIKAHDQKPELHEDLTARERDILKLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDEE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=988871 ACNR93_RS02410 WP_024344653.1 461772..462416(+) (vraR) [Streptococcus equinus strain NM-2-29]
ATGACCCAGAAAATTAGAGTTATCCTAGTTGATGATCATGAAATGGTACGTTTAGGGCTGAAAAGTTTCTTTAATTTGCA
GCCAGACGTTGAAGTTGTCGGTGAAGCTGGAAATGGTATTGATGGGATAAAATTAGCCTTAGAGTTAAAACCAGATGTTG
TTGTTATGGATTTGGTAATGCCAGAGATGAGTGGTGTTGAAGCGACATTGAAGCTTTTAAAAGAGTGGAAAGAAGCCAAA
ATTTTAGTTTTGACATCATACCTTGATAATGAAAAAATTTATCCAGTTATTGAAGCTGGTGCCAAAGGTTACATGCTAAA
AACATCTAGTGCAGCTGAGATTTTAAATGCTATTCATAAAGTTGCGCGTGGTGATTTGGCGATTGAGACAGAAGTTGATA
AAAAAATCAAAGCGCACGATCAAAAACCAGAATTGCATGAGGATCTTACAGCGCGTGAACGAGATATTTTGAAACTTTTG
GCAAAAGGTTATGATAATCAGACTATTGCTGATGAGTTATTTATTTCTCTGAAAACCGTGAAGACACACGTGTCAAATAT
TTTAGCGAAGCTAGAAGTTGATGACCGCACTCAAGCTGTTGTCTATGCCTTTAAGCATCATTTAGTTCCGCAAGATGAGG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.456

96.262

0.495
  degU Bacillus subtilis subsp. subtilis str. 168

37.5

100

0.393