Detailed information    

insolico Bioinformatically predicted

Overview

Name   pptA   Type   Regulator
Locus tag   R8570_RS02305 Genome accession   NZ_AP026932
Coordinates   466878..467609 (+) Length   243 a.a.
NCBI ID   WP_000889919.1    Uniprot ID   A0A062WNF5
Organism   Streptococcus pneumoniae strain PZ900701549     
Function   export ComS (predicted from homology)   
Competence regulation

Genomic Context

Location: 461878..472609
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8570_RS02280 - 463441..464074 (+) 634 Protein_447 DJ-1/PfpI family protein -
  R8570_RS02285 (PC1528_04550) dnaJ 464244..465380 (+) 1137 WP_001066288.1 molecular chaperone DnaJ -
  R8570_RS02290 (PC1528_04560) - 465702..465941 (-) 240 WP_001813906.1 hypothetical protein -
  R8570_RS02295 (PC1528_04570) - 466103..466390 (-) 288 WP_000777760.1 hypothetical protein -
  R8570_RS02300 (PC1528_04580) - 466400..466810 (-) 411 WP_001278301.1 HIT family protein -
  R8570_RS02305 (PC1528_04590) pptA 466878..467609 (+) 732 WP_000889919.1 ABC transporter ATP-binding protein Regulator
  R8570_RS02310 (PC1528_04600) - 467606..468655 (+) 1050 WP_000653771.1 ABC transporter permease -
  R8570_RS02315 (PC1528_04610) - 468823..469152 (-) 330 WP_000132572.1 hypothetical protein -
  R8570_RS02320 (PC1528_04620) - 469429..469767 (+) 339 WP_000682132.1 LytTR family DNA-binding domain-containing protein -
  R8570_RS02325 (PC1528_04630) comE/blpR 469772..470509 (+) 738 WP_001219146.1 response regulator transcription factor Regulator
  R8570_RS02330 (PC1528_04640) - 470523..471863 (+) 1341 WP_001099895.1 sensor histidine kinase -
  R8570_RS02335 (PC1528_04650) blpC 471908..472063 (-) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27012.49 Da        Isoelectric Point: 4.7737

>NTDB_id=98878 R8570_RS02305 WP_000889919.1 466878..467609(+) (pptA) [Streptococcus pneumoniae strain PZ900701549]
MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTINEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIP
ETPSLYEELTLREHIETVAMAYGIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQLREAFDMPEASLNDIYLALTKE
EDL

Nucleotide


Download         Length: 732 bp        

>NTDB_id=98878 R8570_RS02305 WP_000889919.1 466878..467609(+) (pptA) [Streptococcus pneumoniae strain PZ900701549]
ATGTTAGAAATTAAAAACCTGACAGGTGGCTATGTTCATGTTCCTGTTTTGAAAGATGTGTCCTTTACTGTTGAAAGTGG
GCAGCTGGTCGGTTTGATTGGTCTCAATGGTGCTGGGAAATCAACGACGATCAATGAGATTATCGGTCTGTTGGCACCTT
ATAGTGGCTCCATCAATATCAATGGCCTGACTCTGCAAGGAGATGCGACTAGCTACCGCAAGCAGATTGGCTACATTCCT
GAGACGCCTAGTCTGTATGAGGAATTGACCCTCAGAGAGCATATCGAAACGGTTGCTATGGCTTACGGTATTGAGCAAAA
AGTGGCTTTCGAACGAGTAGAGCCCTTGTTAAAGATGTTCCGTCTGGACCAGAAATTAGACTGGTTCCCTGTTCATTTTT
CAAAAGGGATGAAGCAGAAGGTCATGATTATCTGTGCTTTTGTGGTGGATCCAAGTCTTTTCATCGTGGATGAGCCTTTC
CTTGGTCTTGATCCGCTGGCTATTTCTGATTTGATTCAGCTTTTGGAAGTGGAGAAGCAAAAGGGCAAGTCTATTCTCAT
GAGTACCCACGTGCTGGATTCGGCGGAGAAGATGTGTGATGCCTTTGTCATTCTTCACAAGGGAGAGGTGCGTGCCAAAG
GCAATCTCCTGCAACTACGCGAAGCCTTTGATATGCCTGAGGCTAGTTTGAATGATATTTACTTGGCTCTGACAAAAGAG
GAGGACCTATGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(17-160)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A062WNF5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pptA Streptococcus salivarius strain HSISS4

72.614

99.177

0.72
  pptA Streptococcus thermophilus LMD-9

71.784

99.177

0.712

Multiple sequence alignment