Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R8624_RS01785 Genome accession   NZ_AP026930
Coordinates   344235..344924 (+) Length   229 a.a.
NCBI ID   WP_000518010.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701208     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 339235..349924
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8624_RS01760 (PC1195_03380) gpsB 339368..339697 (+) 330 WP_000146522.1 cell division regulator GpsB -
  R8624_RS01770 (PC1195_03390) - 340183..341340 (+) 1158 WP_000711388.1 class I SAM-dependent RNA methyltransferase -
  R8624_RS01775 (PC1195_03400) mapZ 341353..342723 (+) 1371 WP_050311817.1 mid-cell-anchored protein MapZ -
  R8624_RS01780 (PC1195_03410) gndA 342799..344223 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  R8624_RS01785 (PC1195_03420) covR 344235..344924 (+) 690 WP_000518010.1 response regulator transcription factor Regulator
  R8624_RS01790 (PC1195_03430) cbpC 345022..345978 (+) 957 WP_317650214.1 choline-binding protein CbpC -
  R8624_RS01795 (PC1195_03440) mvk 346100..346978 (+) 879 WP_000163315.1 mevalonate kinase -
  R8624_RS01800 (PC1195_03450) mvaD 346960..347913 (+) 954 WP_000373460.1 diphosphomevalonate decarboxylase -
  R8624_RS01805 (PC1195_03460) - 347900..348907 (+) 1008 WP_000562436.1 phosphomevalonate kinase -
  R8624_RS01810 (PC1195_03470) fni 348891..349901 (+) 1011 WP_000210610.1 type 2 isopentenyl-diphosphate Delta-isomerase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26862.16 Da        Isoelectric Point: 6.9836

>NTDB_id=98723 R8624_RS01785 WP_000518010.1 344235..344924(+) (covR) [Streptococcus pneumoniae strain PZ900701208]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTIQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=98723 R8624_RS01785 WP_000518010.1 344235..344924(+) (covR) [Streptococcus pneumoniae strain PZ900701208]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTACAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATTCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment