Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   R8623_RS07175 Genome accession   NZ_AP026928
Coordinates   1415287..1416519 (-) Length   410 a.a.
NCBI ID   WP_000106343.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700406     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1410287..1421519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8623_RS07145 (PC0401_14120) - 1410474..1411442 (+) 969 WP_000081003.1 NAD(P)/FAD-dependent oxidoreductase -
  R8623_RS07150 (PC0401_14130) whiA 1411476..1412387 (-) 912 WP_000011310.1 DNA-binding protein WhiA -
  R8623_RS07155 (PC0401_14140) - 1412384..1413361 (-) 978 WP_001231086.1 YvcK family protein -
  R8623_RS07160 (PC0401_14150) rapZ 1413358..1414248 (-) 891 WP_000163033.1 RNase adapter RapZ -
  R8623_RS07165 (PC0401_14160) - 1414300..1414680 (-) 381 WP_001140412.1 RidA family protein -
  R8623_RS07170 (PC0401_14170) yihA 1414691..1415278 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  R8623_RS07175 (PC0401_14180) clpX 1415287..1416519 (-) 1233 WP_000106343.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  R8623_RS07180 - 1416551..1416721 (-) 171 WP_000442275.1 hypothetical protein -
  R8623_RS07185 (PC0401_14190) - 1416721..1417227 (-) 507 WP_000162486.1 dihydrofolate reductase -
  R8623_RS07190 (PC0401_14200) - 1417357..1417875 (-) 519 WP_000229874.1 DNA starvation/stationary phase protection protein -
  R8623_RS07195 (PC0401_14210) lytC 1418371..1419876 (-) 1506 WP_078140653.1 choline binding-anchored murein hydrolase LytC -
  R8623_RS07200 (PC0401_14220) tpiA 1419914..1420672 (-) 759 WP_000087897.1 triose-phosphate isomerase -
  R8623_RS07205 (PC0401_14230) - 1420771..1421448 (-) 678 WP_000221584.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45825.38 Da        Isoelectric Point: 4.4550

>NTDB_id=98591 R8623_RS07175 WP_000106343.1 1415287..1416519(-) (clpX) [Streptococcus pneumoniae strain PZ900700406]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKNENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=98591 R8623_RS07175 WP_000106343.1 1415287..1416519(-) (clpX) [Streptococcus pneumoniae strain PZ900700406]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATACTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAATGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.965

98.049

0.559

Multiple sequence alignment