Detailed information NTG0985904

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ACN3CX_RS09215
• Genome accession: NZ_CP184461
• Coordinates: 2068966..2070240 (-)
• Length: 424 a.a.
• NCBI ID: WP_015444406.1
• Uniprot ID: Q5ZUE0
• Organism: Legionella pneumophila subsp. pneumophila strain Lp02 dksA1
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2063966..2075240

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACN3CX_RS09205 (ACN3CX_09205)	-	2065871..2066149 (-)	279	WP_011214112.1	HU family DNA-binding protein	-
ACN3CX_RS09210 (ACN3CX_09210)	lon	2066278..2068728 (-)	2451	WP_010947583.1	endopeptidase La	-
ACN3CX_RS09215 (ACN3CX_09215)	clpX	2068966..2070240 (-)	1275	WP_015444406.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ACN3CX_RS09220 (ACN3CX_09220)	clpP	2070381..2071025 (-)	645	WP_010947585.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	-
ACN3CX_RS09225 (ACN3CX_09225)	tig	2071028..2072359 (-)	1332	WP_010947586.1	trigger factor	-
ACN3CX_RS09250 (ACN3CX_09250)	-	2073221..2074447 (+)	1227	WP_010947587.1	tyrosine-type recombinase/integrase	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46583.17 Da
• Isoelectric Point: 5.1603

>NTDB_id=985904 ACN3CX_RS09215 WP_015444406.1 2068966..2070240(-) (clpX) [Legionella pneumophila subsp. pneumophila strain Lp02 dksA1]
MSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVIGQ
QHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENII
QKLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSN
ILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEAAL
IDILTRPKNALTKQFQSLFKMEGSELEFRGEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESV
VNGLSKPILIYEQDEKKSASGSKD

Nucleotide

• Length: 1275 bp

>NTDB_id=985904 ACN3CX_RS09215 WP_015444406.1 2068966..2070240(-) (clpX) [Legionella pneumophila subsp. pneumophila strain Lp02 dksA1]
ATGAGTAAATCCGGTAACGGAAATGGAGATAAGGTCTTATATTGCTCTTTTTGTGGCAAGAGTCAACATGAGGTAAAAAA
ATTAATTGCTGGACCTTCTGTGTTTGTTTGTGATGAATGTGTAGAGCTTTGTAATGATATTATTCGAGAAGAGACGCATG
AAACTCATGAAGAAACTGAGGCACGTCTACCGACACCAAAAGAAATATCTAACTTTCTCGATGAATACGTAATAGGGCAA
CAACATGCCAAAAAGGTTTTATCAGTAGCAGTATATAATCACTATAAGAGATTACAGCATAAAAGCGAGGATGGTGTTGA
GCTCGGCAAAAGTAATATTTTACTTATAGGACCTACTGGCAGTGGTAAGACTCTTTTAGCTCAAACCCTGGCGCGGATTC
TTAATGTTCCTTTTGCCATGGCTGATGCCACGACCCTTACTGAAGCTGGATATGTTGGCGAAGACGTTGAAAATATTATC
CAGAAGTTATTACAGAAGTGCGACTATGATGTAGATAAGGCACAGCAAGGTATTGTCTATATCGACGAAATCGATAAGAT
TTCACGCAAATCAGATAATCCATCTATCACCAGAGATGTTTCAGGAGAAGGTGTTCAACAAGCTTTACTGAAATTAATTG
AAGGTACTGTTGCATCTGTTCCACCGCAAGGTGGGCGAAAGCATCCACAGCAGGAATTTTTGCAGGTAGATACATCAAAT
ATTTTATTTATCTGTGGTGGCGCTTTTGCAGGTTTGGACAAAGTAATACGTGAACGCAGCGATAAATCAAGCATAGGTTT
TTCTGCTCAATTAAAAAGCAAAAAAAGCAGTAATGATGAAGTTTCAAAAGTTTTAGGTCAATTGGAATCAGATGATTTAA
TTAAATATGGGTTGATTCCCGAGTTTGTTGGACGTTTGCCTGTTGTAACCACTTTACAGGAACTTGATGAAGCGGCATTG
ATTGATATATTAACGAGACCTAAGAATGCTTTAACAAAGCAATTTCAATCACTTTTCAAAATGGAAGGTTCTGAACTTGA
GTTTAGAGGCGAAGCTTTGATTGCTATTGCTAAAAAGGCCCTCGAAAGAAAAATGGGCGCAAGAGGTTTGCGATCAATAC
TTGAAAATATTCTTTTAGACACTATGTATGACTTACCTTCCTTGGAAGGCGTGAATAAGGTTGTTATTGATGAGAGTGTA
GTGAATGGACTATCTAAACCGATTCTCATTTATGAACAGGATGAGAAAAAAAGTGCGTCTGGTAGTAAAGATTAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-308)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (315-387)

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

3D structure

• AlphaFold DB: Q5ZUE0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.658	96.462	0.575
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	54.926	95.755	0.526