Detailed information NTG0985745

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: ACOAKG_RS24260
• Genome accession: NZ_CP184261
• Coordinates: 5409955..5411079 (-)
• Length: 374 a.a.
• NCBI ID: WP_030958303.1
• Uniprot ID: A0A7H8T8E1
• Organism: Streptomyces sp. JL3001
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 5404955..5416079

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOAKG_RS24235 (ACOAKG_24235)	-	5405171..5405761 (-)	591	WP_330358607.1	hypothetical protein	-
ACOAKG_RS24240 (ACOAKG_24240)	-	5405920..5406459 (-)	540	WP_030961701.1	SigE family RNA polymerase sigma factor	-
ACOAKG_RS24245 (ACOAKG_24245)	-	5406773..5407711 (-)	939	WP_330355609.1	A/G-specific adenine glycosylase	-
ACOAKG_RS24250 (ACOAKG_24250)	-	5408334..5408756 (+)	423	WP_420076771.1	hypothetical protein	-
ACOAKG_RS24255 (ACOAKG_24255)	-	5409046..5409879 (+)	834	WP_330355611.1	hypothetical protein	-
ACOAKG_RS24260 (ACOAKG_24260)	disA	5409955..5411079 (-)	1125	WP_030958303.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
ACOAKG_RS24265 (ACOAKG_24265)	radA/sms	5411160..5412569 (-)	1410	WP_420076772.1	DNA repair protein RadA	Machinery gene
ACOAKG_RS24270 (ACOAKG_24270)	-	5412785..5414596 (+)	1812	WP_406254738.1	BACON domain-containing protein	-
ACOAKG_RS24275 (ACOAKG_24275)	-	5414635..5415495 (-)	861	WP_359451246.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40110.79 Da
• Isoelectric Point: 4.9201

>NTDB_id=985745 ACOAKG_RS24260 WP_030958303.1 5409955..5411079(-) (disA) [Streptomyces sp. JL3001]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERVLRGNTGGLIVLGFDKTVESMSTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQFVPDATIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALYELDALTHAELLELPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=985745 ACOAKG_RS24260 WP_030958303.1 5409955..5411079(-) (disA) [Streptomyces sp. JL3001]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGCGGGAGTTCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCGGTGGCTCCCGGCACCGCCTTGCGCGACGGGCTCGAACGCGTCCTGCGCGGCAACACCGGCGGACTCATCGTGC
TCGGCTTCGACAAGACCGTCGAGTCGATGAGCACGGGCGGATTCGTCCTGGATGTCGAGTTCACGGCGACGCGGCTGCGT
GAGCTGTGCAAGCTCGACGGCGGCATCGTCCTGTCGTCCGACCTGTCGAAGATCCTTCGCGCGGGTGTGCAGTTCGTGCC
GGACGCGACGATCCCCACGGAGGAGACCGGCACCCGGCACCGCACGGCGGACCGGGTCAGCAAGCAGGTCGGCTTCCCGG
TCGTCTCGGTCTCCCAGTCGATGCGGCTGATCGCGCTCTACGTCGACGGTCAGCGCCGCGTCCTGGAGGACTCGGCGGCG
ATCCTGTCCCGCGCCAACCAGGCCCTCGCGACCCTGGAGCGCTACAAGCTCCGCCTGGACGAGGTCGCGGGAACGTTGTC
AGCGCTGGAGATCGAGGACCTGGTGACGGTCCGCGACGTCTCGGCGGTGGCGCAGCGCCTGGAGATGGTCCGGCGCATTG
CGACCGAGATCGCCGAGTACGTGGTGGAGCTGGGCACCGACGGGCGTCTCCTCGCCCTCCAGCTGGACGAGTTGATCGCG
GGCGTGGAGCCCGAGCGCGAGCTCGTGGTGCGCGACTACGTCCCCGAGCCGACGGCCAAGCGCTCCCGCACGGTCGACGA
GGCGCTGTACGAACTGGACGCGCTCACCCACGCCGAGCTGCTCGAACTGCCCACGGTGGCAAGGGCGTTGGGCTACACCG
GCTCTCCGGAGGCGCTGGACTCGGCGGTCTCCCCGCGCGGCTTCCGTCTGCTGGCCAAGGTGCCCAGGCTGCCCGGCGCG
ATCATCGACCGCCTGGTGGAGCACTTCGGCGGCCTCCAGAAGCTGCTCGCCGCCAGCGTGGACGACCTCCAGACGGTCGA
CGGCGTCGGCGAGGCCCGGGCACGCAGCGTCCGCGAGGGCCTGTCACGGCTGGCGGAGAGCTCGATCCTGGAACGGTACG
TCTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

3D structure

• AlphaFold DB: A0A7H8T8E1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.706	96.524	0.441