Detailed information    

insolico Bioinformatically predicted

Overview

Name   spo0A   Type   Regulator
Locus tag   MKX52_RS10850 Genome accession   NZ_CP152014
Coordinates   2136631..2137434 (-) Length   267 a.a.
NCBI ID   WP_012010520.1    Uniprot ID   W6IDW7
Organism   Bacillus sp. FSL R5-0422     
Function   activation and repression of comK; repression of rok; repression of abrB (predicted from homology)   
Competence regulation

Genomic Context

Location: 2131631..2142434
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKX52_RS10830 (MKX52_10830) - 2133835..2134071 (+) 237 WP_012010516.1 DUF2627 domain-containing protein -
  MKX52_RS10835 (MKX52_10835) - 2134107..2134844 (-) 738 WP_251184290.1 glycerophosphodiester phosphodiesterase -
  MKX52_RS10840 (MKX52_10840) - 2135074..2136174 (-) 1101 WP_251184289.1 Rap family tetratricopeptide repeat protein -
  MKX52_RS10845 (MKX52_10845) - 2136162..2136359 (-) 198 WP_041815709.1 hypothetical protein -
  MKX52_RS10850 (MKX52_10850) spo0A 2136631..2137434 (-) 804 WP_012010520.1 sporulation transcription factor Spo0A Regulator
  MKX52_RS10855 (MKX52_10855) spoIVB 2137720..2138997 (-) 1278 WP_342490687.1 SpoIVB peptidase -
  MKX52_RS10860 (MKX52_10860) recN 2139196..2140932 (-) 1737 WP_144504026.1 DNA repair protein RecN Machinery gene
  MKX52_RS10865 (MKX52_10865) argR 2140966..2141415 (-) 450 WP_012010523.1 transcriptional regulator ArgR -
  MKX52_RS10870 (MKX52_10870) - 2141576..2142430 (-) 855 WP_342490688.1 TlyA family RNA methyltransferase -

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 29918.44 Da        Isoelectric Point: 6.3913

>NTDB_id=984970 MKX52_RS10850 WP_012010520.1 2136631..2137434(-) (spo0A) [Bacillus sp. FSL R5-0422]
MEKIKVCVADDNRELVGLLTEYIEGQEDMEVLGVAYNGQECLTLFKDKEPDVLLLDIIMPHLDGLAVLERLRENNDMTKQ
PSVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLVGHIRQVSGNGTQVTHRSSSIQNSVLRNKPEPKRKNLDASITTI
IHEIGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTV
SMSKAKPTNSEFIAMVADRLRLEHRAS

Nucleotide


Download         Length: 804 bp        

>NTDB_id=984970 MKX52_RS10850 WP_012010520.1 2136631..2137434(-) (spo0A) [Bacillus sp. FSL R5-0422]
GTGGAGAAAATTAAAGTGTGTGTAGCTGATGACAATCGAGAGCTTGTTGGCCTTTTGACAGAGTATATTGAGGGACAGGA
AGATATGGAAGTACTTGGCGTGGCGTATAATGGTCAGGAATGTCTGACATTATTTAAAGATAAAGAGCCCGACGTTCTCC
TCTTAGATATTATCATGCCTCATTTAGATGGCCTTGCTGTACTGGAACGCCTCCGTGAAAACAATGACATGACCAAACAG
CCAAGTGTGATTATGCTAACAGCGTTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGATTTGGGCGCATCTTATTTCAT
CTTAAAGCCATTTGATATGGAAAACCTAGTCGGTCATATTCGTCAAGTCAGTGGAAACGGCACACAAGTCACCCATCGAT
CTTCATCTATCCAAAACAGTGTTCTTCGAAATAAACCTGAACCAAAACGTAAAAACTTAGATGCGAGCATTACGACGATT
ATTCATGAGATTGGCGTACCCGCTCATATTAAAGGTTACTTATACTTAAGAGAAGCCATCTCAATGGTGTACAATGACAT
CGAGCTTCTCGGAAGCATCACAAAAGTGTTGTATCCAGATATCGCGAAGAAATTTAACACGACCGCTAGCAGAGTAGAAC
GAGCAATTCGTCATGCGATTGAAGTGGCTTGGAGCAGAGGAAACATCGATTCCATTTCCTCACTCTTTGGTTATACAGTC
AGCATGTCTAAAGCAAAACCAACCAATTCTGAATTTATCGCAATGGTGGCTGATCGTCTACGCTTGGAGCATAGAGCTAG
CTAG

Domains

Predicted by InterproScan.

Sporulation initiation factor Spo0A C terminal (Spo0A_C)

(157-260)

Response regulator receiver domain (Response_reg)

(6-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W6IDW7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  spo0A Bacillus subtilis subsp. subtilis str. 168

88.433

100

0.888

Multiple sequence alignment