Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R8559_RS10030 Genome accession   NZ_AP026926
Coordinates   1918453..1919406 (-) Length   317 a.a.
NCBI ID   WP_000345123.1    Uniprot ID   A0A0U0M6F6
Organism   Streptococcus pneumoniae strain PZ900700119     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1913453..1924406
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8559_RS10000 (PC0116_19520) - 1914214..1914837 (-) 624 WP_000932644.1 hypothetical protein -
  R8559_RS10005 (PC0116_19530) jag 1914888..1915874 (-) 987 WP_000260025.1 RNA-binding cell elongation regulator Jag/EloR -
  R8559_RS10010 (PC0116_19540) - 1915893..1916717 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  R8559_RS10015 (PC0116_19550) rnpA 1916692..1917063 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R8559_RS10020 - 1917080..1917211 (-) 132 WP_000768903.1 hypothetical protein -
  R8559_RS10025 (PC0116_19560) - 1917212..1918402 (-) 1191 WP_000167759.1 acetate kinase -
  R8559_RS10030 (PC0116_19570) comYH 1918453..1919406 (-) 954 WP_000345123.1 class I SAM-dependent methyltransferase Machinery gene
  R8559_RS10035 (PC0116_19580) - 1919467..1920054 (-) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  R8559_RS10040 (PC0116_19590) comGG/cglG 1920191..1920604 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8559_RS10045 (PC0116_19600) comGF/cglF 1920582..1921043 (-) 462 WP_000250548.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8559_RS10050 (PC0116_19610) comGE/cglE 1921006..1921308 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8559_RS10055 (PC0116_19620) comGD/cglD 1921271..1921675 (-) 405 WP_000588007.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8559_RS10060 (PC0116_19630) comGC/cglC 1921668..1921934 (-) 267 WP_050123149.1 competence type IV pilus major pilin ComGC Machinery gene
  R8559_RS10065 (PC0116_19640) - 1921936..1922193 (-) 258 WP_000698513.1 hypothetical protein -
  R8559_RS10070 (PC0116_19650) - 1922463..1923419 (-) 957 WP_317639174.1 N-acetylmuramoyl-L-alanine amidase family protein -
  R8559_RS10075 (PC0116_19660) - 1923422..1923757 (-) 336 WP_050200954.1 phage holin -
  R8559_RS10080 (PC0116_19670) - 1923761..1924060 (-) 300 WP_001811580.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35747.95 Da        Isoelectric Point: 4.2434

>NTDB_id=98457 R8559_RS10030 WP_000345123.1 1918453..1919406(-) (comYH) [Streptococcus pneumoniae strain PZ900700119]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMVDVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=98457 R8559_RS10030 WP_000345123.1 1918453..1919406(-) (comYH) [Streptococcus pneumoniae strain PZ900700119]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCAGATGCCATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAATGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGTAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0U0M6F6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.313

98.738

0.536
  comYH Streptococcus mutans UA159

53.994

98.738

0.533

Multiple sequence alignment