Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACN9L2_RS09575 Genome accession   NZ_CP184045
Coordinates   2009794..2010450 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 1439     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2004794..2015450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACN9L2_RS09545 (ACN9L2_09545) dcyD 2005673..2006659 (+) 987 WP_001128232.1 D-cysteine desulfhydrase -
  ACN9L2_RS09550 (ACN9L2_09550) tcyL 2006674..2007342 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACN9L2_RS09555 (ACN9L2_09555) tcyN 2007339..2008091 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACN9L2_RS09560 (ACN9L2_09560) sdiA 2008321..2009043 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  ACN9L2_RS09565 (ACN9L2_09565) yecF 2009111..2009335 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACN9L2_RS09570 (ACN9L2_09570) yecU 2009322..2009498 (-) 177 WP_001307856.1 protein YecU -
  ACN9L2_RS09575 (ACN9L2_09575) letA 2009794..2010450 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACN9L2_RS09580 (ACN9L2_09580) uvrC 2010447..2012279 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACN9L2_RS09585 (ACN9L2_09585) pgsA 2012336..2012884 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACN9L2_RS09605 (ACN9L2_09605) - 2013876..2014157 (+) 282 WP_001303543.1 hypothetical protein -
  ACN9L2_RS09610 (ACN9L2_09610) - 2014346..2014486 (-) 141 WP_000078920.1 Hok/Gef family protein -
  ACN9L2_RS09615 (ACN9L2_09615) - 2014678..2014938 (-) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=984298 ACN9L2_RS09575 WP_000611328.1 2009794..2010450(+) (letA) [Escherichia coli strain 1439]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=984298 ACN9L2_RS09575 WP_000611328.1 2009794..2010450(+) (letA) [Escherichia coli strain 1439]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment