Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R8507_RS01820 Genome accession   NZ_AP026925
Coordinates   342617..343306 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700097     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 337617..348306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8507_RS01795 (PC0094_03460) gpsB 337727..338056 (+) 330 WP_000200643.1 cell division regulator GpsB -
  R8507_RS01805 (PC0094_03470) - 338542..339699 (+) 1158 WP_000711388.1 class I SAM-dependent RNA methyltransferase -
  R8507_RS01810 (PC0094_03480) mapZ 339711..341105 (+) 1395 WP_219589058.1 cell division site-positioning protein MapZ family protein -
  R8507_RS01815 (PC0094_03490) gndA 341181..342605 (+) 1425 WP_000158788.1 NADP-dependent phosphogluconate dehydrogenase -
  R8507_RS01820 (PC0094_03500) covR 342617..343306 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  R8507_RS01825 (PC0094_03510) cbpC 343404..344420 (+) 1017 WP_000771103.1 choline-binding protein CbpC -
  R8507_RS01830 (PC0094_03520) mvk 344542..345420 (+) 879 WP_000163315.1 mevalonate kinase -
  R8507_RS01835 (PC0094_03530) mvaD 345402..346355 (+) 954 WP_000373461.1 diphosphomevalonate decarboxylase -
  R8507_RS01840 (PC0094_03540) - 346342..347349 (+) 1008 WP_000562412.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=98328 R8507_RS01820 WP_000518018.1 342617..343306(+) (covR) [Streptococcus pneumoniae strain PZ900700097]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=98328 R8507_RS01820 WP_000518018.1 342617..343306(+) (covR) [Streptococcus pneumoniae strain PZ900700097]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment