Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACN2AT_RS14590 Genome accession   NZ_CP183238
Coordinates   2800087..2801859 (-) Length   590 a.a.
NCBI ID   WP_003246045.1    Uniprot ID   P14951
Organism   Bacillus subtilis strain NDmed     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2795087..2806859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACN2AT_RS14570 (ACN2AT_14475) sdhA 2795306..2797066 (-) 1761 WP_003229567.1 succinate dehydrogenase flavoprotein subunit -
  ACN2AT_RS14575 (ACN2AT_14480) sdhC 2797100..2797708 (-) 609 WP_003222512.1 succinate dehydrogenase cytochrome B558 -
  ACN2AT_RS14580 (ACN2AT_14485) yslB 2798001..2798447 (+) 447 WP_003222508.1 YslB family protein -
  ACN2AT_RS14585 (ACN2AT_14490) lysCA 2798491..2799717 (-) 1227 WP_003229564.1 aspartate kinase -
  ACN2AT_RS14590 (ACN2AT_14495) uvrC 2800087..2801859 (-) 1773 WP_003246045.1 excinuclease ABC subunit UvrC Machinery gene
  ACN2AT_RS14595 (ACN2AT_14500) trxA 2801995..2802309 (-) 315 WP_003222500.1 thioredoxin -
  ACN2AT_RS14600 (ACN2AT_14505) abfB 2802632..2804119 (-) 1488 WP_004398654.1 alpha-L-arabinofuranosidase AbfB -
  ACN2AT_RS14605 (ACN2AT_14510) etfA 2804336..2805313 (-) 978 WP_004398999.1 electron transfer flavoprotein subunit alpha -
  ACN2AT_RS14610 (ACN2AT_14515) etfB 2805349..2806122 (-) 774 WP_004398765.1 electron transfer flavoprotein subunit beta -

Sequence

Protein


Download         Length: 590 a.a.        Molecular weight: 68472.27 Da        Isoelectric Point: 9.4732

>NTDB_id=982831 ACN2AT_RS14590 WP_003246045.1 2800087..2801859(-) (uvrC) [Bacillus subtilis strain NDmed]
MNKQLKEKLALLPDQPGCYLMKDRQQTVIYVGKAKVLKNRVRSYFTGSHDAKTQRLVTEIEDFEYIVTSSNLEALILEMN
LIKKHDPKYNVMLKDDKTYPFIKLTHERHPRLIVTRNVKKDKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCL
YYHLGQCLAPCVKDISEETNRELVESITRFLRGGYNEVKKELEEKMHEAAENLEFERAKELRDQIAHIESTMEKQKMTMN
DLVDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSMFPLYQEADEEFLTFIGQFYSKNNHFLPKEILVPDSIDQSMIEQL
LETNVHQPKKGPKKELLMLAHKNAKIALKEKFSLIERDEERSIGAVQKLGEALNIYTPHRIEAFDNSNIQGTNPVSAMIV
FIDGKPYKKEYRKYKIKTVTGPDDYGSMREVVRRRYTRVLRENLPLPDLIIIDGGKGQINAARDVIENELGLDIPIAGLA
KDEKHRTSNLLIGDPLEVAYLERNSQEFYLLQRIQDEVHRFAISFHRQIRGKSAFQSVLDDIPGIGEKRKKMLLKHFGSV
KKMKEASLEDIKKAGVPAAAAQLLYDKLQK

Nucleotide


Download         Length: 1773 bp        

>NTDB_id=982831 ACN2AT_RS14590 WP_003246045.1 2800087..2801859(-) (uvrC) [Bacillus subtilis strain NDmed]
ATGAACAAACAACTGAAAGAAAAACTCGCCCTCCTTCCTGATCAACCGGGTTGTTATCTCATGAAGGACCGGCAGCAGAC
TGTGATCTACGTAGGGAAAGCAAAAGTGCTGAAAAACAGAGTGCGCTCCTACTTCACCGGTTCTCACGACGCGAAAACCC
AAAGGCTTGTGACGGAAATCGAGGATTTTGAATATATTGTGACGTCCTCCAATCTTGAAGCGCTTATTTTAGAAATGAAT
CTGATCAAAAAGCATGATCCGAAATACAACGTCATGCTCAAAGACGACAAAACCTATCCTTTCATAAAACTCACCCATGA
ACGCCACCCAAGGCTGATTGTCACCCGCAATGTCAAAAAAGACAAAGGGCGCTATTTCGGGCCGTATCCGAATGTACAGG
CAGCAAGGGAAACAAAAAAACTGCTCGACCGTCTGTATCCTCTCAGAAAATGCTCCAAGCTCCCGGACAGAGTGTGCCTT
TACTATCATCTGGGCCAATGCCTTGCTCCGTGTGTAAAGGATATTTCCGAAGAGACGAACAGAGAGCTGGTTGAAAGCAT
TACACGTTTCTTAAGGGGCGGCTATAATGAGGTCAAAAAAGAGCTTGAAGAGAAAATGCATGAAGCTGCTGAGAATCTTG
AGTTTGAACGAGCAAAAGAGCTTCGTGACCAAATTGCCCATATTGAATCAACGATGGAAAAACAAAAAATGACGATGAAC
GATCTAGTCGACCGTGATGTGTTCGCGTACGCGTACGATAAGGGCTGGATGTGCGTGCAGGTCTTTTTCATCCGCCAAGG
AAAGCTCATTGAACGCGATGTCAGCATGTTCCCGCTTTATCAGGAAGCAGATGAAGAGTTCCTCACGTTCATCGGGCAGT
TCTATTCAAAAAACAACCACTTCCTTCCGAAGGAGATTTTAGTTCCGGACAGCATAGATCAATCTATGATCGAGCAGCTA
CTGGAAACAAACGTTCACCAGCCGAAAAAAGGCCCGAAAAAAGAACTGCTCATGCTTGCCCATAAAAATGCGAAAATCGC
ATTGAAAGAAAAATTCTCTTTAATCGAACGGGACGAGGAGCGTTCAATCGGGGCAGTGCAGAAACTAGGTGAGGCATTAA
ATATTTATACGCCGCACAGAATTGAAGCGTTTGATAACTCAAATATACAGGGGACAAACCCGGTTTCCGCGATGATTGTG
TTTATCGATGGCAAACCATACAAAAAGGAATACCGCAAATATAAAATCAAAACTGTTACAGGGCCGGATGATTACGGTTC
TATGAGAGAGGTTGTCAGAAGACGCTATACGAGAGTGCTTCGTGAGAATCTGCCGCTGCCCGATCTGATTATCATTGACG
GAGGAAAAGGGCAGATCAACGCAGCAAGGGATGTCATTGAAAATGAACTCGGCTTGGATATCCCGATCGCCGGTTTAGCG
AAAGATGAAAAACACAGAACCTCAAATTTACTGATCGGTGATCCGCTGGAGGTGGCGTATCTGGAACGAAACAGCCAGGA
ATTTTACCTCCTGCAGCGCATTCAGGACGAGGTGCACCGTTTTGCAATCAGTTTTCACAGGCAAATCCGGGGAAAAAGCG
CGTTTCAATCCGTTTTGGACGACATCCCGGGTATCGGAGAGAAAAGAAAGAAAATGCTGTTAAAGCATTTCGGTTCCGTT
AAAAAAATGAAGGAAGCAAGCCTTGAGGACATCAAAAAAGCCGGTGTTCCCGCAGCGGCGGCTCAGCTCCTTTACGACAA
ATTGCAAAAATAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(373-523)

GIY-YIG catalytic domain (GIY-YIG)

(16-90)

UvrB/uvrC motif (UVR)

(197-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P14951

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

59.354

99.661

0.592
  uvrC Streptococcus pneumoniae R6

59.014

99.661

0.588
  uvrC Streptococcus pneumoniae D39

59.014

99.661

0.588

Multiple sequence alignment