Detailed information NTG0098283

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: R8635_RS09470
• Genome accession: NZ_AP026924
• Coordinates: 1841989..1843056 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159562.1
• Uniprot ID: B1I897
• Organism: Streptococcus pneumoniae strain PZ900700063
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1836989..1848056

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8635_RS09450 (PC0062_18820)	-	1837127..1837609 (+)	483	WP_000032550.1	S-ribosylhomocysteine lyase	-
R8635_RS09455 (PC0062_18830)	-	1838073..1839419 (+)	1347	WP_268217916.1	IS1380-like element ISSpn5 family transposase	-
R8635_RS09460	-	1839701..1840977 (+)	1277	Protein_1879	ISL3 family transposase	-
R8635_RS09465 (PC0062_18860)	amiF	1841052..1841978 (-)	927	WP_001291294.1	ATP-binding cassette domain-containing protein	Regulator
R8635_RS09470 (PC0062_18870)	amiE	1841989..1843056 (-)	1068	WP_000159562.1	ABC transporter ATP-binding protein	Regulator
R8635_RS09475 (PC0062_18880)	amiD	1843065..1843991 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
R8635_RS09480 (PC0062_18890)	amiC	1843991..1845487 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
R8635_RS09485 (PC0062_18900)	amiA3	1845554..1847533 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39504.11 Da
• Isoelectric Point: 4.8764

>NTDB_id=98283 R8635_RS09470 WP_000159562.1 1841989..1843056(-) (amiE) [Streptococcus pneumoniae strain PZ900700063]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKEWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=98283 R8635_RS09470 WP_000159562.1 1841989..1843056(-) (amiE) [Streptococcus pneumoniae strain PZ900700063]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGAGTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: B1I897

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	87.887	100	0.879
amiE	Streptococcus thermophilus LMG 18311	86.197	100	0.862
amiE	Streptococcus thermophilus LMD-9	86.197	100	0.862
oppD	Streptococcus mutans UA159	54.261	99.155	0.538