Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R8635_RS09290 Genome accession   NZ_AP026924
Coordinates   1799987..1800676 (-) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700063     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1794987..1805676
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8635_RS11625 - 1795661..1795783 (-) 123 Protein_1842 hypothetical protein -
  R8635_RS11630 - 1795823..1795990 (-) 168 Protein_1843 transposase -
  R8635_RS09275 - 1796601..1797476 (+) 876 Protein_1844 lanthionine synthetase LanC family protein -
  R8635_RS09280 - 1797519..1798751 (+) 1233 WP_000765691.1 MFS transporter -
  R8635_RS09285 (PC0062_18500) cbpC 1798869..1799888 (-) 1020 WP_268217905.1 choline-binding protein CbpC -
  R8635_RS09290 (PC0062_18510) covR 1799987..1800676 (-) 690 WP_000518011.1 response regulator transcription factor Regulator
  R8635_RS09295 (PC0062_18520) gndA 1800688..1802112 (-) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  R8635_RS09300 (PC0062_18530) mapZ 1802188..1803582 (-) 1395 WP_023396578.1 mid-cell-anchored protein MapZ -
  R8635_RS09305 (PC0062_18540) - 1803595..1804752 (-) 1158 WP_000711393.1 class I SAM-dependent RNA methyltransferase -
  R8635_RS09315 (PC0062_18550) gpsB 1805238..1805567 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=98279 R8635_RS09290 WP_000518011.1 1799987..1800676(-) (covR) [Streptococcus pneumoniae strain PZ900700063]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=98279 R8635_RS09290 WP_000518011.1 1799987..1800676(-) (covR) [Streptococcus pneumoniae strain PZ900700063]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment