Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R8625_RS01790 Genome accession   NZ_AP026923
Coordinates   342618..343307 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700054     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 337618..348307
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8625_RS01765 (PC0054_03420) gpsB 337727..338056 (+) 330 WP_000146522.1 cell division regulator GpsB -
  R8625_RS01775 (PC0054_03430) - 338542..339699 (+) 1158 WP_000711385.1 class I SAM-dependent RNA methyltransferase -
  R8625_RS01780 (PC0054_03440) mapZ 339712..341106 (+) 1395 WP_000039270.1 mid-cell-anchored protein MapZ -
  R8625_RS01785 (PC0054_03450) gndA 341182..342606 (+) 1425 WP_000158794.1 NADP-dependent phosphogluconate dehydrogenase -
  R8625_RS01790 (PC0054_03460) covR 342618..343307 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  R8625_RS01795 (PC0054_03470) cbpC 343405..344427 (+) 1023 WP_317649268.1 choline-binding protein CbpC -
  R8625_RS01800 (PC0054_03480) cbpC 344446..345465 (+) 1020 WP_317649269.1 choline-binding protein CbpC -
  R8625_RS01805 (PC0054_03490) - 345583..346815 (-) 1233 WP_115346848.1 MFS transporter -
  R8625_RS01810 (PC0054_03500) - 346858..347358 (-) 501 WP_142760857.1 lanthionine synthetase LanC family protein -
  R8625_RS01815 (PC0054_03510) - 347345..347610 (-) 266 Protein_355 lantibiotic-modifying protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=98169 R8625_RS01790 WP_000518011.1 342618..343307(+) (covR) [Streptococcus pneumoniae strain PZ900700054]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=98169 R8625_RS01790 WP_000518011.1 342618..343307(+) (covR) [Streptococcus pneumoniae strain PZ900700054]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment