Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   R8586_RS09775 Genome accession   NZ_AP026922
Coordinates   1860790..1861410 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain PZ900700038     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1855790..1866410
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8586_RS09750 (PC0038_19300) recA 1856168..1857334 (-) 1167 WP_001085462.1 recombinase RecA Machinery gene
  R8586_RS09755 (PC0038_19310) cinA 1857389..1858645 (-) 1257 WP_000642703.1 competence/damage-inducible protein A Machinery gene
  R8586_RS09760 (PC0038_19320) brpA 1858729..1859745 (-) 1017 WP_000239285.1 biofilm formation/cell division transcriptional regulator BrpA -
  R8586_RS09765 (PC0038_19330) - 1859753..1860271 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  R8586_RS09770 (PC0038_19340) tsaE 1860261..1860704 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R8586_RS09775 (PC0038_19350) comM 1860790..1861410 (-) 621 WP_000839908.1 hypothetical protein Regulator
  R8586_RS09780 (PC0038_19360) - 1861793..1862563 (-) 771 WP_225415938.1 helix-turn-helix domain-containing protein -
  R8586_RS09785 (PC0038_19370) - 1862845..1863015 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  R8586_RS09790 (PC0038_19380) - 1863330..1863626 (+) 297 WP_000911559.1 lactococcin 972 family bacteriocin -
  R8586_RS09795 (PC0038_19390) - 1863729..1865744 (+) 2016 WP_000732389.1 DUF1430 domain-containing protein -
  R8586_RS09800 (PC0038_19400) - 1865746..1866378 (+) 633 WP_000571420.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=98133 R8586_RS09775 WP_000839908.1 1860790..1861410(-) (comM) [Streptococcus pneumoniae strain PZ900700038]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=98133 R8586_RS09775 WP_000839908.1 1860790..1861410(-) (comM) [Streptococcus pneumoniae strain PZ900700038]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGGAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment