Detailed information    

insolico Bioinformatically predicted

Overview


Name   rcrP   Type   Regulator
Locus tag   R9C51_RS09475 Genome accession   NZ_AP026921
Coordinates   1829356..1830177 (-) Length   273 a.a.
NCBI ID   WP_000601682.1    Uniprot ID   A0A4K3G7N8
Organism   Streptococcus pneumoniae strain PZ900700027     
Function   regulate competence (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1820913..1845776 1829356..1830177 within 0


Gene organization within MGE regions


Location: 1820913..1845776
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R9C51_RS09405 (PC0027_18500) groL 1820913..1822535 (-) 1623 WP_000031568.1 chaperonin GroEL -
  R9C51_RS09410 (PC0027_18510) groES 1822551..1822835 (-) 285 WP_000917330.1 co-chaperone GroES -
  R9C51_RS09415 (PC0027_18520) ssbB/cilA 1822991..1823386 (-) 396 WP_000282467.1 single-stranded DNA-binding protein Machinery gene
  R9C51_RS09420 (PC0027_18530) - 1823464..1824225 (-) 762 WP_057485735.1 SDR family NAD(P)-dependent oxidoreductase -
  R9C51_RS09425 (PC0027_18540) ytpR 1824258..1824884 (-) 627 WP_000578320.1 YtpR family tRNA-binding protein -
  R9C51_RS09430 (PC0027_18550) - 1824900..1825217 (-) 318 WP_000615767.1 thioredoxin family protein -
  R9C51_RS09435 (PC0027_18560) - 1825214..1825513 (-) 300 WP_001013974.1 DUF4651 domain-containing protein -
  R9C51_RS09440 - 1825711..1825773 (-) 63 WP_219300018.1 hypothetical protein -
  R9C51_RS09445 (PC0027_18570) - 1825798..1825989 (-) 192 WP_000291825.1 cell wall-binding protein -
  R9C51_RS09450 (PC0027_18580) - 1826150..1826824 (-) 675 WP_000725751.1 LiaF transmembrane domain-containing protein -
  R9C51_RS09455 (PC0027_18590) - 1826830..1827276 (-) 447 WP_000776594.1 LytTR family DNA-binding domain-containing protein -
  R9C51_RS09460 - 1827390..1827893 (-) 504 WP_000800928.1 phosphatase PAP2 family protein -
  R9C51_RS09465 (PC0027_18600) - 1827890..1828252 (-) 363 WP_000078805.1 DUF2200 domain-containing protein -
  R9C51_RS09470 (PC0027_18610) - 1828318..1829163 (-) 846 Protein_1859 ATP-binding cassette domain-containing protein -
  R9C51_RS09475 (PC0027_18620) rcrP 1829356..1830177 (-) 822 WP_000601682.1 ABC transporter permease Regulator
  R9C51_RS09480 (PC0027_18630) - 1830194..1830665 (-) 472 Protein_1861 MarR family winged helix-turn-helix transcriptional regulator -
  R9C51_RS09485 (PC0027_18640) - 1830789..1831505 (-) 717 WP_000532876.1 YebC/PmpR family DNA-binding transcriptional regulator -
  R9C51_RS09490 (PC0027_18650) ply 1832388..1833797 (-) 1410 WP_001284356.1 cholesterol-dependent cytolysin pneumolysin -
  R9C51_RS09495 (PC0027_18660) - 1833808..1834218 (-) 411 WP_000595762.1 hypothetical protein -
  R9C51_RS09500 (PC0027_18670) - 1834211..1834819 (-) 609 WP_000083614.1 hypothetical protein -
  R9C51_RS09505 (PC0027_18680) - 1834832..1835290 (-) 459 WP_000186955.1 DUF4231 domain-containing protein -
  R9C51_RS09510 (PC0027_18700) - 1835415..1835814 (+) 400 Protein_1867 transposase family protein -
  R9C51_RS09515 (PC0027_18710) - 1836579..1836839 (-) 261 WP_001209207.1 hypothetical protein -
  R9C51_RS09520 - 1836898..1837449 (-) 552 Protein_1869 hypothetical protein -
  R9C51_RS09525 (PC0027_18740) - 1837439..1837636 (-) 198 WP_000890144.1 hypothetical protein -
  R9C51_RS09530 (PC0027_18750) - 1837640..1838224 (-) 585 WP_023396456.1 hypothetical protein -
  R9C51_RS09535 (PC0027_18760) - 1838632..1839057 (-) 426 WP_050232770.1 hypothetical protein -
  R9C51_RS09540 (PC0027_18770) - 1839188..1839544 (-) 357 Protein_1873 ImmA/IrrE family metallo-endopeptidase -
  R9C51_RS09545 (PC0027_18780) - 1839590..1839796 (-) 207 WP_000366087.1 hypothetical protein -
  R9C51_RS09550 (PC0027_18790) - 1839783..1839944 (-) 162 WP_001055999.1 helix-turn-helix domain-containing protein -
  R9C51_RS09555 (PC0027_18800) lytA 1840290..1841246 (-) 957 WP_050232567.1 N-acetylmuramoyl-L-alanine amidase LytA -
  R9C51_RS09560 (PC0027_18810) - 1841622..1842992 (-) 1371 WP_001036271.1 MATE family efflux transporter -
  R9C51_RS09565 (PC0027_18820) recA 1843299..1844465 (-) 1167 WP_001085462.1 recombinase RecA Machinery gene
  R9C51_RS09570 (PC0027_18830) cinA 1844520..1845776 (-) 1257 WP_000642704.1 competence/damage-inducible protein A Machinery gene

Sequence


Protein


Download         Length: 273 a.a.        Molecular weight: 30604.17 Da        Isoelectric Point: 5.9310

>NTDB_id=98051 R9C51_RS09475 WP_000601682.1 1829356..1830177(-) (rcrP) [Streptococcus pneumoniae strain PZ900700027]
MILLAILFTCFSVYLELEVPTYISKITDLLGSQETNLDELWQPASMMMGMSFLAFLSVVAVGFFASRVAASYTSRLRSDI
FNRVLDYSQTEIKKFSIPSLLTRTTNDITQVQMLITMGLQVVTRGSIMAIWAIGKILGHSEYWLWAVLVVVIVNVLMTTV
LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNLFVNRLMAILNPIMMGISSGLSV
AIYWIGAYVINDAAPIARLPLFSDMIIFMSYAM

Nucleotide


Download         Length: 822 bp        

>NTDB_id=98051 R9C51_RS09475 WP_000601682.1 1829356..1830177(-) (rcrP) [Streptococcus pneumoniae strain PZ900700027]
ATGATTTTACTAGCCATTCTCTTTACTTGCTTTTCGGTCTATCTAGAGTTGGAAGTGCCGACCTATATCTCGAAAATTAC
GGATTTGCTAGGTAGTCAAGAAACTAATTTAGATGAGTTGTGGCAGCCGGCAAGCATGATGATGGGAATGTCCTTTCTTG
CCTTCTTGTCCGTAGTTGCAGTTGGATTTTTTGCATCCCGAGTGGCGGCTTCTTATACTAGTAGGCTGAGAAGTGATATT
TTTAACCGAGTTTTGGATTACTCGCAGACAGAGATTAAGAAATTTTCAATTCCTAGCCTCTTGACGCGTACTACCAATGA
CATTACTCAAGTTCAAATGTTGATTACTATGGGCTTGCAAGTGGTAACGCGTGGTTCAATTATGGCTATCTGGGCTATTG
GGAAGATTTTAGGTCATTCAGAATACTGGCTCTGGGCCGTACTTGTGGTAGTGATTGTCAACGTCCTGATGACGACCGTT
TTGATGACGCTAGCCTTTCCAAAACAGTCCTTGATTCAGGGGTTGACAGATAAACTGAACAGTATCACTCGTGAGAGTTT
AACAGGTATTCGTGTCGTTCGTGCCTACAATGCAGAGGATTATCAAAATGAAAAATTTGCAGCAGTAAATGATGAATTGA
CCCGTTTGAATTTGTTTGTCAACCGTCTTATGGCTATTTTGAATCCTATCATGATGGGGATTTCAAGTGGTTTGAGTGTA
GCGATTTACTGGATTGGGGCCTATGTGATTAACGACGCTGCTCCGATAGCGCGTCTGCCTCTCTTTAGTGACATGATTAT
TTTCATGTCTTATGCCATGTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A4K3G7N8

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rcrP Streptococcus mutans UA159

56.842

100

0.593


Multiple sequence alignment