Detailed information NTG0097979

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R8566_RS10120
• Genome accession: NZ_AP026920
• Coordinates: 1948801..1949811 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain PZ900700014
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1943801..1954811

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8566_RS10095 (PC0014_20020)	-	1945012..1945305 (-)	294	WP_000977371.1	hypothetical protein	-
R8566_RS10100 (PC0014_20030)	-	1945467..1945919 (+)	453	WP_000079148.1	universal stress protein	-
R8566_RS10105 (PC0014_20040)	-	1945954..1947342 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
R8566_RS10110 (PC0014_20050)	-	1947408..1948370 (+)	963	WP_001124777.1	asparaginase	-
R8566_RS10115 (PC0014_20060)	-	1948399..1948737 (-)	339	WP_001092049.1	hypothetical protein	-
R8566_RS10120 (PC0014_20070)	ccpA	1948801..1949811 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
R8566_RS10125 (PC0014_20080)	-	1950237..1950836 (-)	600	WP_000772072.1	response regulator transcription factor	-
R8566_RS10130 (PC0014_20090)	-	1950838..1951935 (-)	1098	WP_000893545.1	sensor histidine kinase	-
R8566_RS10135 (PC0014_20100)	-	1951935..1952672 (-)	738	WP_000832844.1	ABC transporter permease	-
R8566_RS10140 (PC0014_20110)	-	1952674..1953558 (-)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
R8566_RS10145 (PC0014_20120)	-	1953545..1953739 (-)	195	WP_000820179.1	hypothetical protein	-
R8566_RS10150 (PC0014_20130)	-	1953736..1953942 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=97979 R8566_RS10120 WP_000990607.1 1948801..1949811(-) (ccpA) [Streptococcus pneumoniae strain PZ900700014]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=97979 R8566_RS10120 WP_000990607.1 1948801..1949811(-) (ccpA) [Streptococcus pneumoniae strain PZ900700014]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568