Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   R8566_RS01990 Genome accession   NZ_AP026920
Coordinates   376563..377252 (+) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain PZ900700014     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 371563..382252
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8566_RS01965 (PC0014_03840) gpsB 371672..372001 (+) 330 WP_000146522.1 cell division regulator GpsB -
  R8566_RS01975 (PC0014_03850) - 372487..373644 (+) 1158 WP_000711393.1 class I SAM-dependent RNA methyltransferase -
  R8566_RS01980 (PC0014_03860) mapZ 373657..375051 (+) 1395 WP_317642177.1 mid-cell-anchored protein MapZ -
  R8566_RS01985 (PC0014_03870) gndA 375127..376551 (+) 1425 WP_000158793.1 NADP-dependent phosphogluconate dehydrogenase -
  R8566_RS01990 (PC0014_03880) covR 376563..377252 (+) 690 WP_000518008.1 response regulator transcription factor Regulator
  R8566_RS01995 (PC0014_03890) cbpC 377351..378373 (+) 1023 WP_000771050.1 choline-binding protein CbpC -
  R8566_RS02000 (PC0014_03900) cbpJ 378392..379390 (+) 999 WP_000771135.1 choline-binding protein CbpJ -
  R8566_RS02005 (PC0014_03910) - 379508..380740 (-) 1233 WP_000765691.1 MFS transporter -
  R8566_RS02010 (PC0014_03920) - 380783..381658 (-) 876 WP_230400225.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=97935 R8566_RS01990 WP_000518008.1 376563..377252(+) (covR) [Streptococcus pneumoniae strain PZ900700014]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=97935 R8566_RS01990 WP_000518008.1 376563..377252(+) (covR) [Streptococcus pneumoniae strain PZ900700014]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGTAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment