Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   WA044_RS14785 Genome accession   NZ_CP151554
Coordinates   2999628..3000272 (-) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain E69     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 2994628..3005272
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WA044_RS14750 (WA044_14750) - 2995813..2996244 (+) 432 WP_003152066.1 Na(+)/H(+) antiporter subunit B -
  WA044_RS14755 (WA044_14755) - 2996244..2996585 (+) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  WA044_RS14760 (WA044_14760) - 2996578..2998059 (+) 1482 WP_003152061.1 Na+/H+ antiporter subunit D -
  WA044_RS14765 (WA044_14765) - 2998065..2998541 (+) 477 WP_003152059.1 Na+/H+ antiporter subunit E -
  WA044_RS14770 (WA044_14770) - 2998541..2998825 (+) 285 WP_003152057.1 Na(+)/H(+) antiporter subunit F1 -
  WA044_RS14775 (WA044_14775) mnhG 2998809..2999183 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  WA044_RS14780 (WA044_14780) - 2999223..2999606 (-) 384 WP_003152054.1 hotdog fold thioesterase -
  WA044_RS14785 (WA044_14785) comA 2999628..3000272 (-) 645 WP_003152052.1 response regulator transcription factor Regulator
  WA044_RS14790 (WA044_14790) comP 3000353..3002656 (-) 2304 WP_003152050.1 histidine kinase Regulator
  WA044_RS14795 (WA044_14795) comX 3002676..3002855 (-) 180 WP_306383677.1 competence pheromone ComX -
  WA044_RS14800 (WA044_14800) comQ 3002809..3003795 (-) 987 WP_269321599.1 class 1 isoprenoid biosynthesis enzyme Regulator
  WA044_RS14805 (WA044_14805) degQ 3003926..3004066 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  WA044_RS14810 (WA044_14810) - 3004532..3004873 (+) 342 WP_014305721.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=979140 WA044_RS14785 WP_003152052.1 2999628..3000272(-) (comA) [Bacillus velezensis strain E69]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=979140 WA044_RS14785 WP_003152052.1 2999628..3000272(-) (comA) [Bacillus velezensis strain E69]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATCGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAATAAGCTGAATGTCGGCTCCCGAACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864

Multiple sequence alignment