Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACM6AR_RS04770 Genome accession   NZ_CP181164
Coordinates   961989..962708 (+) Length   239 a.a.
NCBI ID   WP_001217723.1    Uniprot ID   -
Organism   Staphylococcus aureus strain AG21-0620     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 956989..967708
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM6AR_RS04745 (ACM6AR_04745) - 957070..958050 (+) 981 WP_000427769.1 ABC transporter ATP-binding protein -
  ACM6AR_RS04750 (ACM6AR_04750) opp4B 958043..959004 (+) 962 Protein_928 oligopeptide ABC transporter permease -
  ACM6AR_RS04755 (ACM6AR_04755) opp4C 959016..959897 (+) 882 WP_001180280.1 oligopeptide ABC transporter permease -
  ACM6AR_RS04760 (ACM6AR_04760) trpS 959939..960928 (-) 990 WP_000448944.1 tryptophan--tRNA ligase -
  ACM6AR_RS04765 (ACM6AR_04765) spxA 961223..961618 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  ACM6AR_RS04770 (ACM6AR_04770) mecA 961989..962708 (+) 720 WP_001217723.1 adaptor protein MecA Regulator
  ACM6AR_RS04775 (ACM6AR_04775) coiA 962829..963815 (+) 987 WP_416197067.1 competence protein CoiA Machinery gene
  ACM6AR_RS04780 (ACM6AR_04780) pepF 963863..965671 (+) 1809 WP_000082725.1 oligoendopeptidase F Regulator
  ACM6AR_RS04785 (ACM6AR_04785) yjbH 966131..966937 (-) 807 WP_000896697.1 protease adaptor protein YjbH -
  ACM6AR_RS04790 (ACM6AR_04790) - 966960..967325 (-) 366 WP_000214070.1 truncated hemoglobin YjbI -

Sequence

Protein


Download         Length: 239 a.a.        Molecular weight: 28285.17 Da        Isoelectric Point: 4.1548

>NTDB_id=979028 ACM6AR_RS04770 WP_001217723.1 961989..962708(+) (mecA) [Staphylococcus aureus strain AG21-0620]
MRIERVDDTTVKLFITYSDIEARGFSREDLWTNRKRGEEFFWSMMDEINEEEDFVVEGPLWIQVHAFEKGVEVTISKSKN
EDMMNMSDDDATDQFDEQVQELLAQTLEGEDQLEELFDQRTKEKEAQGSKRQKSSARKNTRTIIVKFNDLEDVINYAYHS
NPITTEFEDLLYMVDGTYYYAVHFDSHVDQEVINDSYSQLLEFAYPTDRTEVYLNDYAKIIMSHNVTAQVRRYFPETTE

Nucleotide


Download         Length: 720 bp        

>NTDB_id=979028 ACM6AR_RS04770 WP_001217723.1 961989..962708(+) (mecA) [Staphylococcus aureus strain AG21-0620]
ATGAGAATAGAACGAGTAGATGATACAACTGTAAAATTGTTTATAACATATAGCGATATCGAGGCCCGTGGATTTAGTCG
TGAAGATTTATGGACAAATCGCAAACGTGGCGAAGAATTCTTTTGGTCAATGATGGATGAAATTAACGAAGAAGAAGATT
TTGTTGTAGAAGGTCCATTATGGATTCAAGTACATGCCTTTGAAAAAGGTGTCGAAGTCACAATTTCTAAATCTAAAAAT
GAAGATATGATGAATATGTCTGATGATGATGCAACTGATCAATTTGATGAACAAGTTCAAGAATTGTTAGCTCAAACATT
AGAAGGTGAAGATCAATTAGAAGAATTATTCGATCAACGAACAAAAGAAAAAGAAGCTCAAGGTTCTAAACGTCAAAAGT
CTTCAGCACGTAAAAATACAAGAACAATTATTGTGAAATTTAACGATTTAGAAGATGTTATTAATTATGCATATCATAGC
AATCCAATAACTACAGAGTTTGAAGATTTGTTATATATGGTTGATGGTACTTATTATTATGCTGTACATTTTGATAGTCA
TGTTGATCAAGAAGTCATTAATGATAGTTACAGTCAATTGCTTGAATTTGCTTATCCAACAGACAGAACAGAAGTTTATT
TAAATGACTATGCTAAAATAATTATGAGTCATAACGTAACAGCTCAAGTTCGACGTTATTTTCCAGAGACAACTGAATAA

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

37.975

99.163

0.377