Detailed information NTG0097900

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: R8613_RS09745
• Genome accession: NZ_AP026919
• Coordinates: 1867418..1868467 (-)
• Length: 349 a.a.
• NCBI ID: WP_317648238.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700012
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1862418..1873467

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8613_RS09720 (PC0012_18860)	-	1863168..1864499 (-)	1332	WP_000390042.1	hemolysin family protein	-
R8613_RS09725 (PC0012_18870)	endA	1864790..1865614 (-)	825	WP_001036786.1	DNA-entry nuclease EndA	Machinery gene
R8613_RS09730 (PC0012_18880)	-	1865653..1865841 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
R8613_RS09735 (PC0012_18890)	murA	1865834..1867117 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
R8613_RS09740 (PC0012_18900)	-	1867141..1867371 (-)	231	WP_000250392.1	DUF1146 family protein	-
R8613_RS09745 (PC0012_18910)	sepM	1867418..1868467 (-)	1050	WP_317648238.1	SepM family pheromone-processing serine protease	Regulator
R8613_RS09750 (PC0012_18920)	coaD	1868451..1868939 (-)	489	WP_001280745.1	pantetheine-phosphate adenylyltransferase	-
R8613_RS09755 (PC0012_18930)	rsmD	1868929..1869468 (-)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
R8613_RS09760 (PC0012_18940)	asnA	1869533..1870525 (-)	993	WP_000747990.1	aspartate--ammonia ligase	-
R8613_RS09765 (PC0012_18950)	-	1870637..1871320 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
R8613_RS09770 (PC0012_18960)	-	1871376..1872116 (-)	741	WP_000152703.1	RNA methyltransferase	-
R8613_RS09775 (PC0012_18970)	-	1872150..1872428 (+)	279	WP_001174613.1	acylphosphatase	-
R8613_RS09780 (PC0012_18980)	yidC	1872506..1873432 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 38058.24 Da
• Isoelectric Point: 5.0859

>NTDB_id=97900 R8613_RS09745 WP_317648238.1 1867418..1868467(-) (sepM) [Streptococcus pneumoniae strain PZ900700012]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKKQSLIFE

Nucleotide

• Length: 1050 bp

>NTDB_id=97900 R8613_RS09745 WP_317648238.1 1867418..1868467(-) (sepM) [Streptococcus pneumoniae strain PZ900700012]
ATGAAAAAAAAGATTAGATGGCCCTTGTATGTTATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACGGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGGAAGATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAAACAATCCCTAAT
TTTTGAGTGA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (231-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.942	97.994	0.587