Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACM6AC_RS05370 Genome accession   NZ_CP181150
Coordinates   1108981..1110762 (+) Length   593 a.a.
NCBI ID   WP_416152497.1    Uniprot ID   -
Organism   Staphylococcus aureus strain AG21-0600     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1103981..1115762
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM6AC_RS05350 (ACM6AC_05350) polX 1104100..1105812 (+) 1713 WP_154284329.1 DNA polymerase/3'-5' exonuclease PolX -
  ACM6AC_RS05355 (ACM6AC_05355) mutS/mutS2 1105822..1108170 (+) 2349 WP_001249293.1 endonuclease MutS2 Machinery gene
  ACM6AC_RS05360 (ACM6AC_05360) trxA 1108343..1108657 (+) 315 WP_001018928.1 thioredoxin -
  ACM6AC_RS05365 (ACM6AC_05365) - 1108720..1108815 (-) 96 WP_154284328.1 hypothetical protein -
  ACM6AC_RS05370 (ACM6AC_05370) uvrC 1108981..1110762 (+) 1782 WP_416152497.1 excinuclease ABC subunit UvrC Machinery gene
  ACM6AC_RS05375 (ACM6AC_05375) - 1111086..1111700 (+) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  ACM6AC_RS05380 (ACM6AC_05380) sdhA 1111752..1113518 (+) 1767 WP_000818277.1 succinate dehydrogenase flavoprotein subunit -
  ACM6AC_RS05385 (ACM6AC_05385) sdhB 1113518..1114333 (+) 816 WP_000139712.1 succinate dehydrogenase iron-sulfur subunit -
  ACM6AC_RS05390 (ACM6AC_05390) racE 1114569..1115369 (+) 801 WP_001039659.1 glutamate racemase -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68641.31 Da        Isoelectric Point: 9.7442

>NTDB_id=978680 ACM6AC_RS05370 WP_416152497.1 1108981..1110762(+) (uvrC) [Staphylococcus aureus strain AG21-0600]
MEDYKQRIKNKLNVVPIEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSDIQGVDPVSA
MVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIEGIGSKRKTLLLRSF
GSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=978680 ACM6AC_RS05370 WP_416152497.1 1108981..1110762(+) (uvrC) [Staphylococcus aureus strain AG21-0600]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATAGAACCAGGCTGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTAAGAAATCGATTGAGATCATATTTTACGGGTGCTCATGATG
CTAAAACAACGAGACTGGTTGGTGAAATACGTCGTTTTGAGTTTATTGTCACGTCAAGTGAAACAGAGTCACTTTTACTG
GAATTGAATCTGATAAAACAATATCAACCAAGATATAATATATTATTAAAGGATGATAAAAGTTATCCATTTATTAAAAT
TACGAAGGAGAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTGACAAACAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCTGCGCGAGGTCCAAAAAAAGATATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCTAGAACAATTAAAGCTATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTGATATCCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTGTCGACGGTAAACCAGACAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGCCGATACTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAATAA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATAGTACCACTGAAGAAAAA
TAGCCAAGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGGTTCGCAATCACATTTCATAGACAAACACGTC
AAAAGACAGGCTTGAAATCAATCCTTGATGATATTGAGGGTATCGGTAGCAAACGTAAAACATTATTATTACGTTCATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTCGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)

UvrB/uvrC motif (UVR)

(200-233)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

57.094

98.651

0.563
  uvrC Streptococcus pneumoniae TIGR4

57.094

98.651

0.563
  uvrC Streptococcus pneumoniae D39

57.094

98.651

0.563

Multiple sequence alignment